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- W1965486407 abstract "Vagotomized (VX) pigeons studied 2 days after surgery exhibited a significant decrease in cloacal temperature (Tb) and respiratory rate (Rf), and an increase in heart rate (Hf) and metabolic rate (M) at the thermoneutral zone, when compared with sham-operated (SVX) pigeons. The effect of intravenous noradrenaline (NA) on Tb, Rf, Hf and M was examined in SVX and VX-pigeons at 15 degrees C. Following NA administration, the Tb and Rf in the SVX-birds dropped from the preinjection level, but in VX-pigeons, they were not significantly altered. In SVX-pigeons, a total suppression of shivering was apparent following NA-injection, while in the majority of VX-pigeons, shivering was only slightly affected or even increased. The Hf in both SVX- and VX-birds increased following NA-injection. The responses to reserpine were qualitatively similar to NA, although much slower. There were no differences between SVX- and VX-birds with regard to Tb, M and Rf following acetylcholine (ACh) and eserine (Ese) injection. Hf increased after ACh+Ese administration in SVX-pigeons, but in VX-birds, it decreased after an initial surge. Shivering was suppressed for 18-20 min in SVX-birds and 30-50 min in VX-birds. It is suggested that the lack of the hypothermic effect of NA in VX-birds is due to the maintenance of oxygen uptake with unimpaired capacity for shivering." @default.
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- W1965486407 date "1995-05-01" @default.
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- W1965486407 title "Noradrenaline-induced hypothermia is suppressed in the vagotomized cold-exposed pigeon" @default.
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- W1965486407 doi "https://doi.org/10.1016/0300-9629(95)98524-k" @default.
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