Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965501183> ?p ?o ?g. }
- W1965501183 endingPage "41" @default.
- W1965501183 startingPage "35" @default.
- W1965501183 abstract "With an attempt to improve the solubility of poorly water-soluble bioactive compound diosmin, its inclusion complexation was investigated with β-cyclodextrin (β-CD) in the presence and/or absence of ternary component, hydroxypropyl methyl cellulose (HPMC) and polyethylene glycol 6000 (PEG 6000). The complexes of diosmin were prepared by kneading technique. Phase solubility studies confirmed a stoichiometry of 1:1 (diosmin:β-CD) molar ratio with an AL-type of phase solubility curve. The stability constants and complexation efficiency of binary systems were significantly improved in the presence of ternary components HPMC and PEG 6000. The formation of inclusion complexes were confirmed by FTIR, powder XRD, DSC, SEM and 1H NMR spectral analyses. In vitro drug release studies and anti-oxidant activity showed promising results when diosmin was complexed in binary and/or ternary system. These results indicated the suitability of β-CD in enhancing the solubility and in vitro bioactivity of diosmin." @default.
- W1965501183 created "2016-06-24" @default.
- W1965501183 creator A5008353875 @default.
- W1965501183 creator A5015718081 @default.
- W1965501183 creator A5020647630 @default.
- W1965501183 creator A5032847921 @default.
- W1965501183 creator A5049933040 @default.
- W1965501183 creator A5055547190 @default.
- W1965501183 creator A5078282530 @default.
- W1965501183 creator A5087074970 @default.
- W1965501183 date "2014-11-01" @default.
- W1965501183 modified "2023-09-25" @default.
- W1965501183 title "Water soluble binary and ternary complexes of diosmin with β-cyclodextrin: Spectroscopic characterization, release studies and anti-oxidant activity" @default.
- W1965501183 cites W1575748956 @default.
- W1965501183 cites W1966132354 @default.
- W1965501183 cites W1970528096 @default.
- W1965501183 cites W1991774590 @default.
- W1965501183 cites W1993397003 @default.
- W1965501183 cites W2006687519 @default.
- W1965501183 cites W2029966127 @default.
- W1965501183 cites W2057782877 @default.
- W1965501183 cites W2058626506 @default.
- W1965501183 cites W2061963139 @default.
- W1965501183 cites W2062677015 @default.
- W1965501183 cites W2068370169 @default.
- W1965501183 cites W2075268393 @default.
- W1965501183 cites W2078275259 @default.
- W1965501183 cites W2116060738 @default.
- W1965501183 cites W2129555071 @default.
- W1965501183 cites W2160340213 @default.
- W1965501183 doi "https://doi.org/10.1016/j.molliq.2014.08.012" @default.
- W1965501183 hasPublicationYear "2014" @default.
- W1965501183 type Work @default.
- W1965501183 sameAs 1965501183 @default.
- W1965501183 citedByCount "42" @default.
- W1965501183 countsByYear W19655011832015 @default.
- W1965501183 countsByYear W19655011832016 @default.
- W1965501183 countsByYear W19655011832017 @default.
- W1965501183 countsByYear W19655011832018 @default.
- W1965501183 countsByYear W19655011832019 @default.
- W1965501183 countsByYear W19655011832020 @default.
- W1965501183 countsByYear W19655011832021 @default.
- W1965501183 countsByYear W19655011832022 @default.
- W1965501183 countsByYear W19655011832023 @default.
- W1965501183 crossrefType "journal-article" @default.
- W1965501183 hasAuthorship W1965501183A5008353875 @default.
- W1965501183 hasAuthorship W1965501183A5015718081 @default.
- W1965501183 hasAuthorship W1965501183A5020647630 @default.
- W1965501183 hasAuthorship W1965501183A5032847921 @default.
- W1965501183 hasAuthorship W1965501183A5049933040 @default.
- W1965501183 hasAuthorship W1965501183A5055547190 @default.
- W1965501183 hasAuthorship W1965501183A5078282530 @default.
- W1965501183 hasAuthorship W1965501183A5087074970 @default.
- W1965501183 hasConcept C10138342 @default.
- W1965501183 hasConcept C127413603 @default.
- W1965501183 hasConcept C13965031 @default.
- W1965501183 hasConcept C155574463 @default.
- W1965501183 hasConcept C160892712 @default.
- W1965501183 hasConcept C162324750 @default.
- W1965501183 hasConcept C178790620 @default.
- W1965501183 hasConcept C185592680 @default.
- W1965501183 hasConcept C199360897 @default.
- W1965501183 hasConcept C2776964284 @default.
- W1965501183 hasConcept C2778004101 @default.
- W1965501183 hasConcept C2779054382 @default.
- W1965501183 hasConcept C2779433975 @default.
- W1965501183 hasConcept C2780565469 @default.
- W1965501183 hasConcept C41008148 @default.
- W1965501183 hasConcept C42360764 @default.
- W1965501183 hasConcept C43617362 @default.
- W1965501183 hasConcept C54400483 @default.
- W1965501183 hasConcept C64452783 @default.
- W1965501183 hasConceptScore W1965501183C10138342 @default.
- W1965501183 hasConceptScore W1965501183C127413603 @default.
- W1965501183 hasConceptScore W1965501183C13965031 @default.
- W1965501183 hasConceptScore W1965501183C155574463 @default.
- W1965501183 hasConceptScore W1965501183C160892712 @default.
- W1965501183 hasConceptScore W1965501183C162324750 @default.
- W1965501183 hasConceptScore W1965501183C178790620 @default.
- W1965501183 hasConceptScore W1965501183C185592680 @default.
- W1965501183 hasConceptScore W1965501183C199360897 @default.
- W1965501183 hasConceptScore W1965501183C2776964284 @default.
- W1965501183 hasConceptScore W1965501183C2778004101 @default.
- W1965501183 hasConceptScore W1965501183C2779054382 @default.
- W1965501183 hasConceptScore W1965501183C2779433975 @default.
- W1965501183 hasConceptScore W1965501183C2780565469 @default.
- W1965501183 hasConceptScore W1965501183C41008148 @default.
- W1965501183 hasConceptScore W1965501183C42360764 @default.
- W1965501183 hasConceptScore W1965501183C43617362 @default.
- W1965501183 hasConceptScore W1965501183C54400483 @default.
- W1965501183 hasConceptScore W1965501183C64452783 @default.
- W1965501183 hasLocation W19655011831 @default.
- W1965501183 hasOpenAccess W1965501183 @default.
- W1965501183 hasPrimaryLocation W19655011831 @default.
- W1965501183 hasRelatedWork W1554818596 @default.
- W1965501183 hasRelatedWork W1982521339 @default.
- W1965501183 hasRelatedWork W1990937097 @default.
- W1965501183 hasRelatedWork W2025254614 @default.