Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965508728> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W1965508728 abstract "Spreading depression (SD) has been found involved in focal cerebral ischemia which may result in severe or lethal neurological deficits. Electrical recording of SD has been used for acute and long term monitoring of focal cerebral ischemia but with an inherently low resolution. Here, we presented optical intrinsic signal imaging (OISI) to characterize the spontaneous SD waves following permanent middle cerebral artery occlusion (MCAO) in rats with high spatial resolution. During each SD episode, the measured optical reflectance varied regionally: decreased (-12.5±2.8%) in the area near the midline, remained flat (3.1±2.5%) in the lateral region, and increased (12.1±3.6%) in the intermediate cortex. The three types of changes yielded identifications for three biological relevant zones: nonischemic cortex, penumbra and infarct core. Accompanying recurrent SD waves, the suggested penumbral area reduced by about 6.4±2.5% of the whole imaged area per SD event, indicating a growth of the infracted area. Staining with 2% 2,3,5-triphenyltetrazolium chloride (TTC) 4 h post-occlusion proved the infarct cortex to be consistent with the lateral region where the final SD wave did not invade (r=0.86±0.10). The results suggest that OISI based on SD can effectively used to distinguish nonischemic cortex, penumbra and infarct core in the ischemic hemisphere and monitor the development of ischemia with high spatial resolution." @default.
- W1965508728 created "2016-06-24" @default.
- W1965508728 creator A5020460631 @default.
- W1965508728 creator A5041369251 @default.
- W1965508728 creator A5056033605 @default.
- W1965508728 creator A5058615051 @default.
- W1965508728 creator A5071317221 @default.
- W1965508728 date "2007-02-08" @default.
- W1965508728 modified "2023-10-05" @default.
- W1965508728 title "Evaluation the development of focal cerebral ischemia in rats by optical imaging based on the spreading depression signals" @default.
- W1965508728 doi "https://doi.org/10.1117/12.701636" @default.
- W1965508728 hasPublicationYear "2007" @default.
- W1965508728 type Work @default.
- W1965508728 sameAs 1965508728 @default.
- W1965508728 citedByCount "1" @default.
- W1965508728 countsByYear W19655087282017 @default.
- W1965508728 crossrefType "proceedings-article" @default.
- W1965508728 hasAuthorship W1965508728A5020460631 @default.
- W1965508728 hasAuthorship W1965508728A5041369251 @default.
- W1965508728 hasAuthorship W1965508728A5056033605 @default.
- W1965508728 hasAuthorship W1965508728A5058615051 @default.
- W1965508728 hasAuthorship W1965508728A5071317221 @default.
- W1965508728 hasConcept C122356138 @default.
- W1965508728 hasConcept C126322002 @default.
- W1965508728 hasConcept C164705383 @default.
- W1965508728 hasConcept C169760540 @default.
- W1965508728 hasConcept C2775841333 @default.
- W1965508728 hasConcept C2776268601 @default.
- W1965508728 hasConcept C2777348757 @default.
- W1965508728 hasConcept C2777798775 @default.
- W1965508728 hasConcept C2778541695 @default.
- W1965508728 hasConcept C2780577055 @default.
- W1965508728 hasConcept C2781041448 @default.
- W1965508728 hasConcept C2989005 @default.
- W1965508728 hasConcept C500558357 @default.
- W1965508728 hasConcept C541997718 @default.
- W1965508728 hasConcept C71924100 @default.
- W1965508728 hasConcept C86803240 @default.
- W1965508728 hasConceptScore W1965508728C122356138 @default.
- W1965508728 hasConceptScore W1965508728C126322002 @default.
- W1965508728 hasConceptScore W1965508728C164705383 @default.
- W1965508728 hasConceptScore W1965508728C169760540 @default.
- W1965508728 hasConceptScore W1965508728C2775841333 @default.
- W1965508728 hasConceptScore W1965508728C2776268601 @default.
- W1965508728 hasConceptScore W1965508728C2777348757 @default.
- W1965508728 hasConceptScore W1965508728C2777798775 @default.
- W1965508728 hasConceptScore W1965508728C2778541695 @default.
- W1965508728 hasConceptScore W1965508728C2780577055 @default.
- W1965508728 hasConceptScore W1965508728C2781041448 @default.
- W1965508728 hasConceptScore W1965508728C2989005 @default.
- W1965508728 hasConceptScore W1965508728C500558357 @default.
- W1965508728 hasConceptScore W1965508728C541997718 @default.
- W1965508728 hasConceptScore W1965508728C71924100 @default.
- W1965508728 hasConceptScore W1965508728C86803240 @default.
- W1965508728 hasLocation W19655087281 @default.
- W1965508728 hasOpenAccess W1965508728 @default.
- W1965508728 hasPrimaryLocation W19655087281 @default.
- W1965508728 hasRelatedWork W1991007651 @default.
- W1965508728 hasRelatedWork W202920313 @default.
- W1965508728 hasRelatedWork W2067990884 @default.
- W1965508728 hasRelatedWork W2082375799 @default.
- W1965508728 hasRelatedWork W2091411233 @default.
- W1965508728 hasRelatedWork W2132969017 @default.
- W1965508728 hasRelatedWork W2227637901 @default.
- W1965508728 hasRelatedWork W2364597673 @default.
- W1965508728 hasRelatedWork W2378129912 @default.
- W1965508728 hasRelatedWork W2567963980 @default.
- W1965508728 isParatext "false" @default.
- W1965508728 isRetracted "false" @default.
- W1965508728 magId "1965508728" @default.
- W1965508728 workType "article" @default.