FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965513308> ?p ?o ?g. }

• W1965513308 endingPage "581" @default.
• W1965513308 startingPage "578" @default.
• W1965513308 abstract "Background There have been several reports of linkage between genetic markers on the X chromosome at Xq26.3-28 and bipolar affective disorder in family samples obtained from distinct ethnic and geographical origins. As part of a genome search in a series of 23 UK and Icelandic families, specifically selected for their large size and power to resolve the issue of linkage heterogeneity, we have tested the hypothesis that there is a locus for a genetic subtype of bipolar affective disorder which is linked to this region. Method In families selected on the basis of absent male to male transmission for affective disorder, we performed two-point and FASTMAP multipoint linkage analyses with markers spanning the region between the genetic loci DXS102 and F8 Results We found negative lod scores for several models of affection status in families selected under stringent and relaxed criteria for the absence of male to male transmission. Conclusions In the family sample we have obtained, our study provides no support for the presence of a locus increasing genetic susceptibility to bipolar affective disorder in this region of the X chromosome. It is likely that our finding reflects heterogeneity of linkage for bipolar and genetically related unipolar disorder that exists in specific ethnic populations. Alternatively the X-linked subtype of the disorder may have been present only in a few of our small families resulting in loss of power to detect the Xq26.3-28 linked subtype." @default.
• W1965513308 created "2016-06-24" @default.
• W1965513308 creator A5011307949 @default.
• W1965513308 creator A5013153231 @default.
• W1965513308 creator A5032465043 @default.
• W1965513308 creator A5037553646 @default.
• W1965513308 creator A5041313527 @default.
• W1965513308 creator A5055247456 @default.
• W1965513308 creator A5060742914 @default.
• W1965513308 creator A5063408005 @default.
• W1965513308 creator A5079162464 @default.
• W1965513308 creator A5080773436 @default.
• W1965513308 date "1997-12-01" @default.
• W1965513308 modified "2023-09-26" @default.
• W1965513308 title "Test of Xq26.3–28 linkage in bipolar and unipolar affective disorder in families selected for absence of male to male transmission" @default.
• W1965513308 cites W1493988389 @default.
• W1965513308 cites W167992241 @default.
• W1965513308 cites W1964386248 @default.
• W1965513308 cites W1967942132 @default.
• W1965513308 cites W1974702488 @default.
• W1965513308 cites W1977446398 @default.
• W1965513308 cites W1978981523 @default.
• W1965513308 cites W1990246858 @default.
• W1965513308 cites W2000413702 @default.
• W1965513308 cites W2002560522 @default.
• W1965513308 cites W2014839770 @default.
• W1965513308 cites W2017362649 @default.
• W1965513308 cites W2017428806 @default.
• W1965513308 cites W2041404405 @default.
• W1965513308 cites W2045050139 @default.
• W1965513308 cites W2045294941 @default.
• W1965513308 cites W2045927661 @default.
• W1965513308 cites W2048744836 @default.
• W1965513308 cites W2059065009 @default.
• W1965513308 cites W2069717444 @default.
• W1965513308 cites W2118094114 @default.
• W1965513308 cites W2122941998 @default.
• W1965513308 cites W2136204271 @default.
• W1965513308 cites W2154145603 @default.
• W1965513308 cites W2403313799 @default.
• W1965513308 cites W2406319212 @default.
• W1965513308 cites W2413481728 @default.
• W1965513308 doi "https://doi.org/10.1192/bjp.171.6.578" @default.
• W1965513308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9519101" @default.
• W1965513308 hasPublicationYear "1997" @default.
• W1965513308 type Work @default.
• W1965513308 sameAs 1965513308 @default.
• W1965513308 citedByCount "10" @default.
• W1965513308 countsByYear W19655133082012 @default.
• W1965513308 crossrefType "journal-article" @default.
• W1965513308 hasAuthorship W1965513308A5011307949 @default.
• W1965513308 hasAuthorship W1965513308A5013153231 @default.
• W1965513308 hasAuthorship W1965513308A5032465043 @default.
• W1965513308 hasAuthorship W1965513308A5037553646 @default.
• W1965513308 hasAuthorship W1965513308A5041313527 @default.
• W1965513308 hasAuthorship W1965513308A5055247456 @default.
• W1965513308 hasAuthorship W1965513308A5060742914 @default.
• W1965513308 hasAuthorship W1965513308A5063408005 @default.
• W1965513308 hasAuthorship W1965513308A5079162464 @default.
• W1965513308 hasAuthorship W1965513308A5080773436 @default.
• W1965513308 hasConcept C104317684 @default.
• W1965513308 hasConcept C127716648 @default.
• W1965513308 hasConcept C142870003 @default.
• W1965513308 hasConcept C169760540 @default.
• W1965513308 hasConcept C169900460 @default.
• W1965513308 hasConcept C190789776 @default.
• W1965513308 hasConcept C2776174506 @default.
• W1965513308 hasConcept C31266012 @default.
• W1965513308 hasConcept C35158069 @default.
• W1965513308 hasConcept C54355233 @default.
• W1965513308 hasConcept C64618202 @default.
• W1965513308 hasConcept C84597430 @default.
• W1965513308 hasConcept C86803240 @default.
• W1965513308 hasConceptScore W1965513308C104317684 @default.
• W1965513308 hasConceptScore W1965513308C127716648 @default.
• W1965513308 hasConceptScore W1965513308C142870003 @default.
• W1965513308 hasConceptScore W1965513308C169760540 @default.
• W1965513308 hasConceptScore W1965513308C169900460 @default.
• W1965513308 hasConceptScore W1965513308C190789776 @default.
• W1965513308 hasConceptScore W1965513308C2776174506 @default.
• W1965513308 hasConceptScore W1965513308C31266012 @default.
• W1965513308 hasConceptScore W1965513308C35158069 @default.
• W1965513308 hasConceptScore W1965513308C54355233 @default.
• W1965513308 hasConceptScore W1965513308C64618202 @default.
• W1965513308 hasConceptScore W1965513308C84597430 @default.
• W1965513308 hasConceptScore W1965513308C86803240 @default.
• W1965513308 hasIssue "6" @default.
• W1965513308 hasLocation W19655133081 @default.
• W1965513308 hasLocation W19655133082 @default.
• W1965513308 hasOpenAccess W1965513308 @default.
• W1965513308 hasPrimaryLocation W19655133081 @default.
• W1965513308 hasRelatedWork W1482042401 @default.
• W1965513308 hasRelatedWork W1705096185 @default.
• W1965513308 hasRelatedWork W1893536949 @default.
• W1965513308 hasRelatedWork W1991236944 @default.
• W1965513308 hasRelatedWork W2002560522 @default.
• W1965513308 hasRelatedWork W2019648484 @default.
• W1965513308 hasRelatedWork W2026496328 @default.

• next