Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965514225> ?p ?o ?g. }
- W1965514225 endingPage "1777" @default.
- W1965514225 startingPage "1771" @default.
- W1965514225 abstract "Recent studies have revealed that miR-92a is overexpressed in several types of malignancies and provides a protumorigenic effect. Our findings demonstrate that the high expression of miR-92a in human glioma specimens is significantly correlated with low levels of BCL2L11 (Bim) protein and high-grade glioma. Here, we present the first evidence that miR-92a antisense oligonucleotide (AS-miR-92a) provides a tumor suppressive effect via induction of apoptosis in human glioma cells. In addition, we show that Bim is a direct functional target of miR-92a. Introducing Bim cDNA without 3'UTR abrogates miR-92a-induced cell survival. Further investigations will focus on the therapeutic use of AS-miR‑92a-mediated antitumor effects in glioma." @default.
- W1965514225 created "2016-06-24" @default.
- W1965514225 creator A5011553270 @default.
- W1965514225 creator A5030480273 @default.
- W1965514225 creator A5030691366 @default.
- W1965514225 creator A5033873552 @default.
- W1965514225 creator A5037475520 @default.
- W1965514225 creator A5046597133 @default.
- W1965514225 creator A5072691096 @default.
- W1965514225 creator A5088476571 @default.
- W1965514225 creator A5090731919 @default.
- W1965514225 creator A5065308092 @default.
- W1965514225 date "2012-08-10" @default.
- W1965514225 modified "2023-10-14" @default.
- W1965514225 title "miR-92a is a critical regulator of the apoptosis pathway in glioblastoma with inverse expression of BCL2L11" @default.
- W1965514225 cites W1549309132 @default.
- W1965514225 cites W1607015107 @default.
- W1965514225 cites W1969370465 @default.
- W1965514225 cites W1970760326 @default.
- W1965514225 cites W1972755526 @default.
- W1965514225 cites W1980718338 @default.
- W1965514225 cites W1989454102 @default.
- W1965514225 cites W1990079648 @default.
- W1965514225 cites W2001605136 @default.
- W1965514225 cites W2009669110 @default.
- W1965514225 cites W2033019313 @default.
- W1965514225 cites W2036044314 @default.
- W1965514225 cites W2036169252 @default.
- W1965514225 cites W2049001563 @default.
- W1965514225 cites W2052974657 @default.
- W1965514225 cites W2055074145 @default.
- W1965514225 cites W2058462008 @default.
- W1965514225 cites W2068951190 @default.
- W1965514225 cites W2080407932 @default.
- W1965514225 cites W2104381279 @default.
- W1965514225 cites W2112785261 @default.
- W1965514225 cites W2114052327 @default.
- W1965514225 cites W2126669746 @default.
- W1965514225 cites W2134201967 @default.
- W1965514225 cites W2135836598 @default.
- W1965514225 cites W2142310248 @default.
- W1965514225 cites W2147717419 @default.
- W1965514225 cites W2148268378 @default.
- W1965514225 cites W2162128852 @default.
- W1965514225 cites W2168215017 @default.
- W1965514225 doi "https://doi.org/10.3892/or.2012.1970" @default.
- W1965514225 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22895567" @default.
- W1965514225 hasPublicationYear "2012" @default.
- W1965514225 type Work @default.
- W1965514225 sameAs 1965514225 @default.
- W1965514225 citedByCount "49" @default.
- W1965514225 countsByYear W19655142252013 @default.
- W1965514225 countsByYear W19655142252014 @default.
- W1965514225 countsByYear W19655142252015 @default.
- W1965514225 countsByYear W19655142252016 @default.
- W1965514225 countsByYear W19655142252017 @default.
- W1965514225 countsByYear W19655142252018 @default.
- W1965514225 countsByYear W19655142252019 @default.
- W1965514225 countsByYear W19655142252020 @default.
- W1965514225 countsByYear W19655142252021 @default.
- W1965514225 countsByYear W19655142252022 @default.
- W1965514225 countsByYear W19655142252023 @default.
- W1965514225 crossrefType "journal-article" @default.
- W1965514225 hasAuthorship W1965514225A5011553270 @default.
- W1965514225 hasAuthorship W1965514225A5030480273 @default.
- W1965514225 hasAuthorship W1965514225A5030691366 @default.
- W1965514225 hasAuthorship W1965514225A5033873552 @default.
- W1965514225 hasAuthorship W1965514225A5037475520 @default.
- W1965514225 hasAuthorship W1965514225A5046597133 @default.
- W1965514225 hasAuthorship W1965514225A5065308092 @default.
- W1965514225 hasAuthorship W1965514225A5072691096 @default.
- W1965514225 hasAuthorship W1965514225A5088476571 @default.
- W1965514225 hasAuthorship W1965514225A5090731919 @default.
- W1965514225 hasBestOaLocation W19655142251 @default.
- W1965514225 hasConcept C104317684 @default.
- W1965514225 hasConcept C145059251 @default.
- W1965514225 hasConcept C190283241 @default.
- W1965514225 hasConcept C2778227246 @default.
- W1965514225 hasConcept C2781018059 @default.
- W1965514225 hasConcept C29537977 @default.
- W1965514225 hasConcept C502942594 @default.
- W1965514225 hasConcept C55493867 @default.
- W1965514225 hasConcept C6929976 @default.
- W1965514225 hasConcept C86803240 @default.
- W1965514225 hasConceptScore W1965514225C104317684 @default.
- W1965514225 hasConceptScore W1965514225C145059251 @default.
- W1965514225 hasConceptScore W1965514225C190283241 @default.
- W1965514225 hasConceptScore W1965514225C2778227246 @default.
- W1965514225 hasConceptScore W1965514225C2781018059 @default.
- W1965514225 hasConceptScore W1965514225C29537977 @default.
- W1965514225 hasConceptScore W1965514225C502942594 @default.
- W1965514225 hasConceptScore W1965514225C55493867 @default.
- W1965514225 hasConceptScore W1965514225C6929976 @default.
- W1965514225 hasConceptScore W1965514225C86803240 @default.
- W1965514225 hasIssue "5" @default.
- W1965514225 hasLocation W19655142251 @default.
- W1965514225 hasLocation W19655142252 @default.
- W1965514225 hasOpenAccess W1965514225 @default.