Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965536670> ?p ?o ?g. }
- W1965536670 endingPage "174" @default.
- W1965536670 startingPage "167" @default.
- W1965536670 abstract "Mammalian ovaries contain a large number of oocytes, most of which degenerate either before or at various stages of growth. Dynamic and precise regulation in the ovary involves many factors, each with a unique role. Identifying the single most important factor is impossible; however, it may be possible to identify factors essential for oocyte growth. It is evident that oocytes can grow into competent ova in vitro; however, how faithfully the follicle should mimic the in vivo conditions remains unclear. In the culture system discussed in this review, bovine and mouse oocyte-granulosa cell complexes, at approximately the late mid-growth stage, spread on a substratum without the involvement of theca cells. The structural simplicity of this system is advantageous because it reduces the basic conditions essential for regulation of oocyte growth. Apart from biological factors, high concentrations of polyvinylpyrrolidone (molecular weight: 360000) improved oocyte growth. Among ovarian factors, androstenedione was used to compensate for the absence of theca cells, and it promoted both follicular growth and acquisition of oocyte meiotic competence. Most oocytes cultured in a group were viable after long-term culture, suggesting that unlike ovarian events, there was no exhaustive follicle selection. Collectively, oocytes and their associated granulosa cells can establish independent units capable of supporting oocyte growth in appropriately modified culture media." @default.
- W1965536670 created "2016-06-24" @default.
- W1965536670 creator A5033840489 @default.
- W1965536670 date "2012-01-01" @default.
- W1965536670 modified "2023-09-27" @default.
- W1965536670 title "Isolation of Ovarian Components Essential for Growth and Development of Mammalian Oocytes <i>In Vitro</i>" @default.
- W1965536670 cites W1496836538 @default.
- W1965536670 cites W1506916478 @default.
- W1965536670 cites W1600346513 @default.
- W1965536670 cites W1964214826 @default.
- W1965536670 cites W1968446974 @default.
- W1965536670 cites W1972324826 @default.
- W1965536670 cites W1974068706 @default.
- W1965536670 cites W1978702490 @default.
- W1965536670 cites W1988581801 @default.
- W1965536670 cites W1989234418 @default.
- W1965536670 cites W1990122135 @default.
- W1965536670 cites W1993816409 @default.
- W1965536670 cites W1993932453 @default.
- W1965536670 cites W1995235656 @default.
- W1965536670 cites W1997235388 @default.
- W1965536670 cites W1997492405 @default.
- W1965536670 cites W2002530713 @default.
- W1965536670 cites W2005958031 @default.
- W1965536670 cites W2009971819 @default.
- W1965536670 cites W2011074882 @default.
- W1965536670 cites W2011348946 @default.
- W1965536670 cites W2012929661 @default.
- W1965536670 cites W2014724553 @default.
- W1965536670 cites W2018342970 @default.
- W1965536670 cites W2018707834 @default.
- W1965536670 cites W2018933867 @default.
- W1965536670 cites W2019108353 @default.
- W1965536670 cites W2020461250 @default.
- W1965536670 cites W2024372050 @default.
- W1965536670 cites W2027704381 @default.
- W1965536670 cites W2028320284 @default.
- W1965536670 cites W2028967585 @default.
- W1965536670 cites W2038725702 @default.
- W1965536670 cites W2039513998 @default.
- W1965536670 cites W2039707872 @default.
- W1965536670 cites W2040143097 @default.
- W1965536670 cites W2040156011 @default.
- W1965536670 cites W2040182585 @default.
- W1965536670 cites W2042378785 @default.
- W1965536670 cites W2043850967 @default.
- W1965536670 cites W2048762145 @default.
- W1965536670 cites W2048919588 @default.
- W1965536670 cites W2049421708 @default.
- W1965536670 cites W2050147027 @default.
- W1965536670 cites W2052810387 @default.
- W1965536670 cites W2057336811 @default.
- W1965536670 cites W2062895932 @default.
- W1965536670 cites W2065437151 @default.
- W1965536670 cites W2067867779 @default.
- W1965536670 cites W2068604517 @default.
- W1965536670 cites W2069805450 @default.
- W1965536670 cites W2070907274 @default.
- W1965536670 cites W2071552751 @default.
- W1965536670 cites W2075242594 @default.
- W1965536670 cites W2076184271 @default.
- W1965536670 cites W2076565229 @default.
- W1965536670 cites W2076853816 @default.
- W1965536670 cites W2078322680 @default.
- W1965536670 cites W2079307795 @default.
- W1965536670 cites W2087130018 @default.
- W1965536670 cites W2090551120 @default.
- W1965536670 cites W2090562200 @default.
- W1965536670 cites W2093393676 @default.
- W1965536670 cites W2097425334 @default.
- W1965536670 cites W2099469805 @default.
- W1965536670 cites W2100347190 @default.
- W1965536670 cites W2100729936 @default.
- W1965536670 cites W2101398935 @default.
- W1965536670 cites W2101774339 @default.
- W1965536670 cites W2102691716 @default.
- W1965536670 cites W2102826720 @default.
- W1965536670 cites W2105393662 @default.
- W1965536670 cites W2111508487 @default.
- W1965536670 cites W2111833649 @default.
- W1965536670 cites W2112945113 @default.
- W1965536670 cites W2113164000 @default.
- W1965536670 cites W2118162811 @default.
- W1965536670 cites W2121898993 @default.
- W1965536670 cites W2122459288 @default.
- W1965536670 cites W2125318362 @default.
- W1965536670 cites W2126952151 @default.
- W1965536670 cites W2127483452 @default.
- W1965536670 cites W2128865345 @default.
- W1965536670 cites W2130897208 @default.
- W1965536670 cites W2132560878 @default.
- W1965536670 cites W2133200515 @default.
- W1965536670 cites W2135067530 @default.
- W1965536670 cites W2136932385 @default.
- W1965536670 cites W2137946016 @default.
- W1965536670 cites W2140338076 @default.
- W1965536670 cites W2141167215 @default.
- W1965536670 cites W2142250901 @default.