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- W1965543330 abstract "Clopidogrel is a thienopyridine derivative with a relatively low occurrence of adverse side effects. Increasing evidence, however, suggests that clopidogrel may cause severe liver injury. Until now, five cases of clopidogrel-induced acute hepatitis have been reported. We describe the case of an 80-year-old man who developed symptomatic liver disease 6 weeks after 1x75 mg/day clopidogrel intake as adjunctive antiplatelet therapy for a renal artery stent implantation. Histological examination revealed severe acute hepatitis with extensive hepatocanalicular cholestasis and focal cell necrosis with a preferential zone-3 distribution of hepatic damage. In the present paper, we describe the clinico-histopathological characteristics of a case of clopidogrel-induced acute hepatitis and discuss the current literature." @default.
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- W1965543330 date "2006-08-01" @default.
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- W1965543330 title "Clinico-histopathological characteristics of clopidogrel-induced hepatic injury: case report and review of literature" @default.
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- W1965543330 doi "https://doi.org/10.1097/00042737-200608000-00022" @default.
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