FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965614166> ?p ?o ?g. }

• W1965614166 endingPage "134" @default.
• W1965614166 startingPage "43" @default.
• W1965614166 abstract "Abstract Despite the proven utility of 113Cd NMR chemical shifts for qualitatively or, in some cases, semiquantitatively assessing the nature of ligands at metal binding sites in metalloproteins and for studying enzyme function and mechanisms, it is likely that the full potential of 113Cd spectroscopy as a metallobioprobe has yet to be realized. The development of a more quantitative relationship between structural parameters and 113Cd chemical shift has been hampered in part by the lack of suitable model compounds and chemical dynamics [6]. As described throughout this review, these challenges are currently being met through applications of solid-state and low-temperature solution NMR methods and the design and study of less labile protein model compounds. However, even for cases where dynamics and solvent or anion effects can be ruled out, it appears that ligand atom type and number, bond lengths, coordination geometry, and neighboring atoms (including other metals) all influence 113Cd shifts. Studies of coordination compounds in solution have thus far provided useful information on the influence of donor-atom type and number on isotropic Cd chemical shifts. The influence on shift of coordination geometry and CdL bond lengths will probably only be adequately evaluated using the single crystal approach pioneered by Ellis and co-workers. Studies of the Cd ion bound exclusively by O-donor ligands will likely also be only adequately addressed through solid-state NMR methods due to lability problems with these ligands. In this area, model compounds with O-donor ligands which exhibit the unusual high-field shifts found for ICaBP and HRP are lacking. 113Cd NMR chemical shift information alone is at present inadequate for unambiguous determination of structural features or structural changes at the metal binding sites of metalloproteins. In this regard, HMQC NMR spectroscopy promises to be a particularly useful tool for identifying the ligands which are coordinated to Cd. For cases where ligand exchange or nuclear relaxation rates are high (relative to 1/J), however, this method will not work and determination of structural features may rely exclusively on chemical shift analyses. It is therefore important that both techniques be developed and utilized." @default.
• W1965614166 created "2016-06-24" @default.
• W1965614166 creator A5002027818 @default.
• W1965614166 date "1988-05-01" @default.
• W1965614166 modified "2023-10-02" @default.
• W1965614166 title "113Cd NMR spectroscopy of coordination compounds and proteins" @default.
• W1965614166 cites W1482263734 @default.
• W1965614166 cites W1485285854 @default.
• W1965614166 cites W1486693351 @default.
• W1965614166 cites W1490343705 @default.
• W1965614166 cites W1495782235 @default.
• W1965614166 cites W1517794943 @default.
• W1965614166 cites W1544251830 @default.
• W1965614166 cites W1562687679 @default.
• W1965614166 cites W1568041976 @default.
• W1965614166 cites W1570602397 @default.
• W1965614166 cites W1571581590 @default.
• W1965614166 cites W1572492375 @default.
• W1965614166 cites W1577128492 @default.
• W1965614166 cites W1594494653 @default.
• W1965614166 cites W1595139970 @default.
• W1965614166 cites W1601013567 @default.
• W1965614166 cites W1608883348 @default.
• W1965614166 cites W1670756326 @default.
• W1965614166 cites W1965607587 @default.
• W1965614166 cites W1967194512 @default.
• W1965614166 cites W1970818486 @default.
• W1965614166 cites W1971810720 @default.
• W1965614166 cites W1973559719 @default.
• W1965614166 cites W1974435560 @default.
• W1965614166 cites W1974780824 @default.
• W1965614166 cites W1975694787 @default.
• W1965614166 cites W1975811365 @default.
• W1965614166 cites W1979837091 @default.
• W1965614166 cites W1980597251 @default.
• W1965614166 cites W1980775511 @default.
• W1965614166 cites W1985030315 @default.
• W1965614166 cites W1985334115 @default.
• W1965614166 cites W1986193410 @default.
• W1965614166 cites W1989876822 @default.
• W1965614166 cites W1990820869 @default.
• W1965614166 cites W1991132143 @default.
• W1965614166 cites W1991406025 @default.
• W1965614166 cites W1998951716 @default.
• W1965614166 cites W2000870176 @default.
• W1965614166 cites W2001224094 @default.
• W1965614166 cites W2002151844 @default.
• W1965614166 cites W2002931031 @default.
• W1965614166 cites W2004730328 @default.
• W1965614166 cites W2005769064 @default.
• W1965614166 cites W2006468177 @default.
• W1965614166 cites W2008136965 @default.
• W1965614166 cites W2010244519 @default.
• W1965614166 cites W2010305148 @default.
• W1965614166 cites W2010381876 @default.
• W1965614166 cites W2010978824 @default.
• W1965614166 cites W2011820865 @default.
• W1965614166 cites W2012400755 @default.
• W1965614166 cites W2012570871 @default.
• W1965614166 cites W2014565362 @default.
• W1965614166 cites W2017442048 @default.
• W1965614166 cites W2018752610 @default.
• W1965614166 cites W2020861880 @default.
• W1965614166 cites W2024163805 @default.
• W1965614166 cites W2024290940 @default.
• W1965614166 cites W2028438917 @default.
• W1965614166 cites W2028915419 @default.
• W1965614166 cites W2030788726 @default.
• W1965614166 cites W2031020991 @default.
• W1965614166 cites W2033673061 @default.
• W1965614166 cites W2033690073 @default.
• W1965614166 cites W2034452233 @default.
• W1965614166 cites W2034602222 @default.
• W1965614166 cites W2035725159 @default.
• W1965614166 cites W2036458465 @default.
• W1965614166 cites W2037292798 @default.
• W1965614166 cites W2038404805 @default.
• W1965614166 cites W2038844755 @default.
• W1965614166 cites W2039059793 @default.
• W1965614166 cites W2039930406 @default.
• W1965614166 cites W2042546325 @default.
• W1965614166 cites W2046291488 @default.
• W1965614166 cites W2049291146 @default.
• W1965614166 cites W2050305266 @default.
• W1965614166 cites W2054522487 @default.
• W1965614166 cites W2055049220 @default.
• W1965614166 cites W2056137342 @default.
• W1965614166 cites W2057514708 @default.
• W1965614166 cites W2058560995 @default.
• W1965614166 cites W2059790256 @default.
• W1965614166 cites W2063655141 @default.
• W1965614166 cites W2065253200 @default.
• W1965614166 cites W2065973288 @default.
• W1965614166 cites W2066369636 @default.
• W1965614166 cites W2067523885 @default.
• W1965614166 cites W2067550505 @default.
• W1965614166 cites W2069461840 @default.
• W1965614166 cites W2070009684 @default.

• next