Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965622164> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1965622164 endingPage "449" @default.
- W1965622164 startingPage "442" @default.
- W1965622164 abstract "The characteristics of pituitary hormonal responses to insulin-induced hypoglycemia were investigated in 16 normal men. In all subjects, levels of blood sugar fell below 35 mg/100 ml. A statistically significant increase in mean plasma levels of prolactin, ACTH, cortisol and growth hormone was observed. Prolactin levels increased in all subjects but one; individual peak values were 1.4 minus 8.4 times greater than base levels. The kinetics of prolactin, GH and ACTH responses were similar; in particular, the onset of release (25 min) of prolactin, GH and ACTH was similar. After dexamethasone administration, insulin tolerance tests wererepeated in a number of subjects using adequate amounts of insulin to achieve hypoglycemia equivalent to that obtained in the control experiments. The administration of 1 mg of dexamethasone the evening before the test suppressed basal levels of ACTH and cortisol and the ACTH-but not the cortisol-response to hypoglycemia. Both basal levels of prolactin and prolactin response to hypoglycemia were significantly lowered but growth hormone response was not modified by administration of 1 mg of dexamethasone. The administration of larger doses of dexamethasone (1 mg every 6 h for 2 days) almost completely suppressed basal levels of ACTH, cortisol and prolactin, as well as the hypoglycemia-induced release of these hormones. In contrast, the growth hormone response to hypoglycemia was only partially inhibited. These findings demonstrate that both basal secretion and hypoglycemia-induced release of prolactin, ACTH, cortisol and growth hormone are suppressible by glucocorticoids." @default.
- W1965622164 created "2016-06-24" @default.
- W1965622164 creator A5013491878 @default.
- W1965622164 creator A5021555454 @default.
- W1965622164 creator A5035033819 @default.
- W1965622164 creator A5065884697 @default.
- W1965622164 creator A5068211240 @default.
- W1965622164 creator A5082571059 @default.
- W1965622164 creator A5085731788 @default.
- W1965622164 date "1975-03-01" @default.
- W1965622164 modified "2023-09-23" @default.
- W1965622164 title "Effects of Glucocorticoids on Pituitary Hormonal Responses to Hypoglycemia. Inhibition of Prolactin Release*" @default.
- W1965622164 cites W2018695869 @default.
- W1965622164 cites W2923359193 @default.
- W1965622164 doi "https://doi.org/10.1210/jcem-40-3-442" @default.
- W1965622164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/163844" @default.
- W1965622164 hasPublicationYear "1975" @default.
- W1965622164 type Work @default.
- W1965622164 sameAs 1965622164 @default.
- W1965622164 citedByCount "115" @default.
- W1965622164 countsByYear W19656221642013 @default.
- W1965622164 countsByYear W19656221642015 @default.
- W1965622164 countsByYear W19656221642023 @default.
- W1965622164 crossrefType "journal-article" @default.
- W1965622164 hasAuthorship W1965622164A5013491878 @default.
- W1965622164 hasAuthorship W1965622164A5021555454 @default.
- W1965622164 hasAuthorship W1965622164A5035033819 @default.
- W1965622164 hasAuthorship W1965622164A5065884697 @default.
- W1965622164 hasAuthorship W1965622164A5068211240 @default.
- W1965622164 hasAuthorship W1965622164A5082571059 @default.
- W1965622164 hasAuthorship W1965622164A5085731788 @default.
- W1965622164 hasBestOaLocation W19656221642 @default.
- W1965622164 hasConcept C126322002 @default.
- W1965622164 hasConcept C134018914 @default.
- W1965622164 hasConcept C2776216936 @default.
- W1965622164 hasConcept C2778024521 @default.
- W1965622164 hasConcept C2778709874 @default.
- W1965622164 hasConcept C2779064019 @default.
- W1965622164 hasConcept C2779306644 @default.
- W1965622164 hasConcept C2780401358 @default.
- W1965622164 hasConcept C2780546910 @default.
- W1965622164 hasConcept C2780668416 @default.
- W1965622164 hasConcept C71315377 @default.
- W1965622164 hasConcept C71924100 @default.
- W1965622164 hasConceptScore W1965622164C126322002 @default.
- W1965622164 hasConceptScore W1965622164C134018914 @default.
- W1965622164 hasConceptScore W1965622164C2776216936 @default.
- W1965622164 hasConceptScore W1965622164C2778024521 @default.
- W1965622164 hasConceptScore W1965622164C2778709874 @default.
- W1965622164 hasConceptScore W1965622164C2779064019 @default.
- W1965622164 hasConceptScore W1965622164C2779306644 @default.
- W1965622164 hasConceptScore W1965622164C2780401358 @default.
- W1965622164 hasConceptScore W1965622164C2780546910 @default.
- W1965622164 hasConceptScore W1965622164C2780668416 @default.
- W1965622164 hasConceptScore W1965622164C71315377 @default.
- W1965622164 hasConceptScore W1965622164C71924100 @default.
- W1965622164 hasIssue "3" @default.
- W1965622164 hasLocation W19656221641 @default.
- W1965622164 hasLocation W19656221642 @default.
- W1965622164 hasLocation W19656221643 @default.
- W1965622164 hasOpenAccess W1965622164 @default.
- W1965622164 hasPrimaryLocation W19656221641 @default.
- W1965622164 hasRelatedWork W1965622164 @default.
- W1965622164 hasRelatedWork W1972415367 @default.
- W1965622164 hasRelatedWork W1992093962 @default.
- W1965622164 hasRelatedWork W2017619841 @default.
- W1965622164 hasRelatedWork W2017802511 @default.
- W1965622164 hasRelatedWork W2033209790 @default.
- W1965622164 hasRelatedWork W2077925316 @default.
- W1965622164 hasRelatedWork W2095933318 @default.
- W1965622164 hasRelatedWork W2150096959 @default.
- W1965622164 hasRelatedWork W2153052119 @default.
- W1965622164 hasVolume "40" @default.
- W1965622164 isParatext "false" @default.
- W1965622164 isRetracted "false" @default.
- W1965622164 magId "1965622164" @default.
- W1965622164 workType "article" @default.