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- W1965639563 abstract "Systemic mastocytosis is rare in children and is characterized by an abnormal proliferation and infiltration of mast cells in different tissues.We report a case of systemic mastocytosis presenting cutaneous symptoms during the neonatal period. Later evolution was characterized by systemic manifestations consisting of recurrent respiratory infections with wheezing and a digestive involvement that included abdominal pain, hepatosplenomegaly and a nodular, hemorrhagic infiltrate in a low esophagus. The diagnosis was confirmed by histology and biology, notably increased histamine concentrations in blood and urines. Improvement of the respiratory and digestive symptoms was obtained with treatment by histamine H1 and H2 receptors antagonists.Respiratory manifestations and nodular infiltration of the digestive tract are rare in systemic mastocytosis. The prognosis is conditioned by complications such as malignancy and the persistence of the disease till the adult age." @default.
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- W1965639563 date "2003-10-01" @default.
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- W1965639563 title "Mastocytose systémique du nourrisson : à propos d’un cas avec atteinte respiratoire et digestive" @default.
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- W1965639563 doi "https://doi.org/10.1016/s0929-693x(03)00458-5" @default.
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