FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965655567> ?p ?o ?g. }

• W1965655567 endingPage "1493" @default.
• W1965655567 startingPage "1487" @default.
• W1965655567 abstract "Approximately 10% to 15% of cases of grade 1 cervical intraepithelial neoplasia are found to have progressed to a high-grade squamous intraepithelial lesion or higher at follow-up, and there are presently no reliable morphological predictors of this subset. It has recently been reported that cases of grade 1 cervical intraepithelial neoplasia that display marked nuclear atypia (defined as cases with at least 5 epithelial cells with nuclear enlargement of at least 5 times the size of an intermediate cell, and/or multinucleation of at least 5 nuclei.) have a substantially higher rate of high-grade squamous intraepithelial lesion on short-term follow-up and may, therefore, require more aggressive initial management. We report herein our experience with a cohort of such cases. After a review of consecutive cervical biopsies, 352 cases with grade 1 cervical intraepithelial neoplasia were classified into group 1 (grade 1 cervical intraepithelial neoplasia with marked atypia, n = 31) and group 2 (grade 1 cervical intraepithelial neoplasia without marked atypia, n = 321). The average follow-up rates for groups 1 and 2 were 93.55% (29/31) and 90.65% (291/321), respectively. Average follow-up durations were 14.3 and 17.9 months, respectively. The follow-up high-grade squamous intraepithelial lesion rate of the cases with marked atypia was 10.34%, as compared with 11.68% for cases without marked atypia. The follow-up interpretive frequency (in cytologic samples) of low-grade squamous intraepithelial lesion was significantly higher in group 1(19/29 versus 114/291, P = .009). However, no significant differences were identified between groups 1 and 2 regarding the interpretive frequencies of either high-grade squamous intraepithelial lesion (3/29 versus 34/291, P = 1) or negative for intraepithelial lesion or malignancy (6/29 versus 56/291, P = .8) in follow-up cytologic samples. In subsets of both groups in which high-risk human papillomavirus testing was performed in the Papanicolaou test sample that immediately preceded the index cervical biopsies, no significant differences in viral load were found. In conclusion, grade 1 cervical intraepithelial neoplasia with marked atypia does not have a higher follow-up high-grade squamous intraepithelial lesion rate than grade 1 cervical intraepithelial neoplasia without marked atypia in our patient population. Further studies are required to address the significance of marked atypia in grade 1 cervical intraepithelial neoplasia and whether patients with this finding should be managed differently." @default.
• W1965655567 created "2016-06-24" @default.
• W1965655567 creator A5043669779 @default.
• W1965655567 creator A5086056909 @default.
• W1965655567 date "2009-10-01" @default.
• W1965655567 modified "2023-09-27" @default.
• W1965655567 title "The significance of marked nuclear atypia in grade 1 cervical intraepithelial neoplasia" @default.
• W1965655567 cites W142540958 @default.
• W1965655567 cites W1996705208 @default.
• W1965655567 cites W2012433524 @default.
• W1965655567 cites W2013856097 @default.
• W1965655567 cites W2018604091 @default.
• W1965655567 cites W2036087634 @default.
• W1965655567 cites W2043103956 @default.
• W1965655567 cites W2043177410 @default.
• W1965655567 cites W2053238499 @default.
• W1965655567 cites W2059976783 @default.
• W1965655567 cites W2063870290 @default.
• W1965655567 cites W2064591289 @default.
• W1965655567 cites W2068415932 @default.
• W1965655567 cites W2093587960 @default.
• W1965655567 cites W2095317270 @default.
• W1965655567 cites W2103347596 @default.
• W1965655567 cites W2114813165 @default.
• W1965655567 cites W2128737857 @default.
• W1965655567 cites W2147114541 @default.
• W1965655567 cites W2322758029 @default.
• W1965655567 cites W3026861555 @default.
• W1965655567 cites W3143504308 @default.
• W1965655567 cites W4251542078 @default.
• W1965655567 cites W4255739412 @default.
• W1965655567 cites W4256145433 @default.
• W1965655567 cites W4362208337 @default.
• W1965655567 doi "https://doi.org/10.1016/j.humpath.2009.03.015" @default.
• W1965655567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19540559" @default.
• W1965655567 hasPublicationYear "2009" @default.
• W1965655567 type Work @default.
• W1965655567 sameAs 1965655567 @default.
• W1965655567 citedByCount "3" @default.
• W1965655567 countsByYear W19656555672013 @default.
• W1965655567 countsByYear W19656555672019 @default.
• W1965655567 countsByYear W19656555672020 @default.
• W1965655567 crossrefType "journal-article" @default.
• W1965655567 hasAuthorship W1965655567A5043669779 @default.
• W1965655567 hasAuthorship W1965655567A5086056909 @default.
• W1965655567 hasConcept C121608353 @default.
• W1965655567 hasConcept C126322002 @default.
• W1965655567 hasConcept C142724271 @default.
• W1965655567 hasConcept C204232928 @default.
• W1965655567 hasConcept C2775924586 @default.
• W1965655567 hasConcept C2776235491 @default.
• W1965655567 hasConcept C2777343196 @default.
• W1965655567 hasConcept C2778220009 @default.
• W1965655567 hasConcept C2779534503 @default.
• W1965655567 hasConcept C2781156865 @default.
• W1965655567 hasConcept C2781283455 @default.
• W1965655567 hasConcept C2781289014 @default.
• W1965655567 hasConcept C71924100 @default.
• W1965655567 hasConceptScore W1965655567C121608353 @default.
• W1965655567 hasConceptScore W1965655567C126322002 @default.
• W1965655567 hasConceptScore W1965655567C142724271 @default.
• W1965655567 hasConceptScore W1965655567C204232928 @default.
• W1965655567 hasConceptScore W1965655567C2775924586 @default.
• W1965655567 hasConceptScore W1965655567C2776235491 @default.
• W1965655567 hasConceptScore W1965655567C2777343196 @default.
• W1965655567 hasConceptScore W1965655567C2778220009 @default.
• W1965655567 hasConceptScore W1965655567C2779534503 @default.
• W1965655567 hasConceptScore W1965655567C2781156865 @default.
• W1965655567 hasConceptScore W1965655567C2781283455 @default.
• W1965655567 hasConceptScore W1965655567C2781289014 @default.
• W1965655567 hasConceptScore W1965655567C71924100 @default.
• W1965655567 hasIssue "10" @default.
• W1965655567 hasLocation W19656555671 @default.
• W1965655567 hasLocation W19656555672 @default.
• W1965655567 hasOpenAccess W1965655567 @default.
• W1965655567 hasPrimaryLocation W19656555671 @default.
• W1965655567 hasRelatedWork W129059858 @default.
• W1965655567 hasRelatedWork W1822658247 @default.
• W1965655567 hasRelatedWork W1965655567 @default.
• W1965655567 hasRelatedWork W1968848158 @default.
• W1965655567 hasRelatedWork W1975390435 @default.
• W1965655567 hasRelatedWork W2156493878 @default.
• W1965655567 hasRelatedWork W2165809227 @default.
• W1965655567 hasRelatedWork W2413795008 @default.
• W1965655567 hasRelatedWork W3026535118 @default.
• W1965655567 hasRelatedWork W2024206645 @default.
• W1965655567 hasVolume "40" @default.
• W1965655567 isParatext "false" @default.
• W1965655567 isRetracted "false" @default.
• W1965655567 magId "1965655567" @default.
• W1965655567 workType "article" @default.