Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965665338> ?p ?o ?g. }
- W1965665338 abstract "Human herpesviruses are widespread infectious pathogens that have been associated with proliferative and inflammatory diseases. During viral evolution, human herpesviruses have pirated genes encoding viral G protein-coupled receptors (vGPCRs), which are expressed on infected host cells. These vGPCRs show highest homology to human chemokine receptors, which play a key role in the immune system. Importantly, vGPCRs have acquired unique properties such as constitutive activity and the ability to bind a broad range of human chemokines. This allows vGPCRs to hijack human proteins and modulate cellular signaling for the benefit of the virus, ultimately resulting in immune evasion and viral dissemination to establish a widespread and lifelong infection. Knowledge on the mechanisms by which herpesviruses reprogram cellular signaling might provide insight in the contribution of vGPCRs to viral survival and herpesvirus-associated pathologies." @default.
- W1965665338 created "2016-06-24" @default.
- W1965665338 creator A5009333831 @default.
- W1965665338 creator A5024847865 @default.
- W1965665338 creator A5060121526 @default.
- W1965665338 creator A5087896916 @default.
- W1965665338 date "2015-03-09" @default.
- W1965665338 modified "2023-10-14" @default.
- W1965665338 title "Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors" @default.
- W1965665338 cites W112392588 @default.
- W1965665338 cites W1483350500 @default.
- W1965665338 cites W1484727384 @default.
- W1965665338 cites W1489775551 @default.
- W1965665338 cites W149440659 @default.
- W1965665338 cites W1499511192 @default.
- W1965665338 cites W1520562583 @default.
- W1965665338 cites W1543291357 @default.
- W1965665338 cites W1543575007 @default.
- W1965665338 cites W1548270485 @default.
- W1965665338 cites W1554666404 @default.
- W1965665338 cites W1579891230 @default.
- W1965665338 cites W1582134010 @default.
- W1965665338 cites W1587318259 @default.
- W1965665338 cites W1601621203 @default.
- W1965665338 cites W1603274157 @default.
- W1965665338 cites W1606957740 @default.
- W1965665338 cites W1613195352 @default.
- W1965665338 cites W1699017532 @default.
- W1965665338 cites W1724443945 @default.
- W1965665338 cites W1787380229 @default.
- W1965665338 cites W1833104430 @default.
- W1965665338 cites W1864251807 @default.
- W1965665338 cites W1877692039 @default.
- W1965665338 cites W1883057908 @default.
- W1965665338 cites W1889694848 @default.
- W1965665338 cites W1897848314 @default.
- W1965665338 cites W1922705469 @default.
- W1965665338 cites W1933410007 @default.
- W1965665338 cites W1964557313 @default.
- W1965665338 cites W1965077874 @default.
- W1965665338 cites W1965223661 @default.
- W1965665338 cites W1966470043 @default.
- W1965665338 cites W1966627438 @default.
- W1965665338 cites W1966940022 @default.
- W1965665338 cites W1966948366 @default.
- W1965665338 cites W1967579128 @default.
- W1965665338 cites W1967767166 @default.
- W1965665338 cites W1968927848 @default.
- W1965665338 cites W1970717080 @default.
- W1965665338 cites W1970741569 @default.
- W1965665338 cites W1971480498 @default.
- W1965665338 cites W1972331061 @default.
- W1965665338 cites W1972712916 @default.
- W1965665338 cites W1973741646 @default.
- W1965665338 cites W1974624016 @default.
- W1965665338 cites W1976641138 @default.
- W1965665338 cites W1977033769 @default.
- W1965665338 cites W1977222310 @default.
- W1965665338 cites W1978831789 @default.
- W1965665338 cites W1980464074 @default.
- W1965665338 cites W1980753190 @default.
- W1965665338 cites W1981493299 @default.
- W1965665338 cites W1981822303 @default.
- W1965665338 cites W1982047106 @default.
- W1965665338 cites W1982913109 @default.
- W1965665338 cites W1983377532 @default.
- W1965665338 cites W1984016730 @default.
- W1965665338 cites W1986959671 @default.
- W1965665338 cites W1987042773 @default.
- W1965665338 cites W1988176721 @default.
- W1965665338 cites W1988743962 @default.
- W1965665338 cites W1989525395 @default.
- W1965665338 cites W1990136945 @default.
- W1965665338 cites W1993655108 @default.
- W1965665338 cites W1995399236 @default.
- W1965665338 cites W1996297229 @default.
- W1965665338 cites W1996829285 @default.
- W1965665338 cites W1998273363 @default.
- W1965665338 cites W1998286599 @default.
- W1965665338 cites W1998340485 @default.
- W1965665338 cites W1999252727 @default.
- W1965665338 cites W1999762190 @default.
- W1965665338 cites W2000343045 @default.
- W1965665338 cites W2001051671 @default.
- W1965665338 cites W2001197100 @default.
- W1965665338 cites W2004314848 @default.
- W1965665338 cites W2005017965 @default.
- W1965665338 cites W2005220388 @default.
- W1965665338 cites W2005970043 @default.
- W1965665338 cites W2006713185 @default.
- W1965665338 cites W2006973742 @default.
- W1965665338 cites W2007134676 @default.
- W1965665338 cites W2007268116 @default.
- W1965665338 cites W2007639993 @default.
- W1965665338 cites W2008116181 @default.
- W1965665338 cites W2008460142 @default.
- W1965665338 cites W2008795750 @default.
- W1965665338 cites W2008848746 @default.
- W1965665338 cites W2009089974 @default.
- W1965665338 cites W2009156962 @default.