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Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965686588> ?p ?o ?g. }

• W1965686588 endingPage "269" @default.
• W1965686588 startingPage "259" @default.
• W1965686588 abstract "Human lymphocytes were treated prior to mitogenic stimulation with varying concentrations of 6 cytostatic drugs representing 4 classes of DNA-damaging chemicals. Afterwards the cells were washed to remove residual chemical and cultured in the presence of bromodeoxyuridine for analysis of sister-chromatid exchanges (SCEs). A dose-related increase in SCEs was observed in cells exposed during G 0 to the alkylating chemicals mitomycin C, chlorambucil, and thiotepa, while significant increases in SCEs were not noted in cultures exposed to methotrexate, cytarabine, or bleomycin. These findings suggest that not all classes of clastogenic chemicals which induce SCEs in proliferative cells substituted with BUdR are capable of inducing long-lived lesions in the DNA of G 0 lymphocytes that can lead to SCE formation." @default.
• W1965686588 created "2016-06-24" @default.
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• W1965686588 date "1979-07-01" @default.
• W1965686588 modified "2023-09-26" @default.
• W1965686588 title "Sister-chromatid exchanges in human lymphocytes exposed during G0 to four classes of DNA-damaging chemicals" @default.
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• W1965686588 doi "https://doi.org/10.1016/0165-1218(79)90020-x" @default.
• W1965686588 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/90341" @default.
• W1965686588 hasPublicationYear "1979" @default.
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