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- W1965717174 abstract "Summary We report on photodynamic therapy with orally and intravesically applied 5-aminolevulinic acid using coherent laser-light or alternatively a white light source in patients with recurrent, multifocal superficial transitional cell carcinoma of the urinary bladder and upper urothelial tract. We determined whether this treatment was effective in destroying urothelial carcinoma and preventing recurrent disease. We also evaluated the side effects of this therapy. The studies shall help define the optimal target group of patients and are considered the basis for long term and multicenter studies. The initial clinical results indicate that photodynamic therapy with 5-aminolevulinic acid is an effective organ-preserving procedure for treating multifocal superficial transitional cell carcinoma of the upper urinary tract and bladder, even in patients with refractory urothelial carcinoma and is effective in selectively destroying flat neoplastic lesions like carcinoma in situ. None of the patients showed phototoxic skin reactions or loss of bladder capacity. To avoid hemodynamic side effects, the intravesical route of 5-aminolevulinic acid application is preferable." @default.
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- W1965717174 date "2003-01-01" @default.
- W1965717174 modified "2023-09-25" @default.
- W1965717174 title "Photodynamic Therapy of Transitional Cell Carcinoma Using 5-Aminolevulinic Acid" @default.
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- W1965717174 doi "https://doi.org/10.1078/1615-1615-00090" @default.
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