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- W1965732013 abstract "Abstract The rodent corticospinal tract is essentially a completely crossed tract which projects down to lumbar levels of the spinal cord. Since its terminations in the spinal cord develop after birth, this experiment was designed to investigate the postnatal development of one corticospinal tract after neonatal surgical ablation of the opposite corticospinal tract. Large hemispheric lesions which destroyed the tract on one side were made in newborn rats. Three to 8 mo later, the opposite frontal cortex was ablated, and animals were killed 3 to 5 days after the second lesion. The staining of degenerated axons demonstrated an aberrant ipsilateral corticospinal projection which was not present in control animals which sustained only adult cortical lesions. It is suggested that this ipsilateral pathway may contribute to recovery mechanisms associated with brain damage in the newborn." @default.
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- W1965732013 date "1975-01-01" @default.
- W1965732013 modified "2023-09-27" @default.
- W1965732013 title "Ipsilateral corticospinal projections after large lesions of the cerebral hemisphere in neonatal rats" @default.
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- W1965732013 doi "https://doi.org/10.1016/0014-4886(75)90026-6" @default.
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