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• W1965742783 endingPage "294" @default.
• W1965742783 startingPage "282" @default.
• W1965742783 abstract "Unlike other immune cells, B cells express both an antigen-specific B cell receptor (BCR) and Toll-like receptors (TLRs). Dual BCR and TLR engagement can fine-tune functional B cell responses, directly linking cell-intrinsic innate and adaptive immune programmes. Although most data regarding B cell-specific functions of the TLR signalling pathway have been obtained in mice, the discovery of patients with a deficiency in this pathway has recently provided an insight into human B cell responses. Here, we highlight the importance of the integration of signalling pathways downstream of BCRs and TLRs in modulating B cell function, focusing when possible on B cell-intrinsic roles." @default.
• W1965742783 created "2016-06-24" @default.
• W1965742783 creator A5011116502 @default.
• W1965742783 creator A5027470095 @default.
• W1965742783 creator A5066561471 @default.
• W1965742783 creator A5067571710 @default.
• W1965742783 date "2012-03-16" @default.
• W1965742783 modified "2023-10-17" @default.
• W1965742783 title "Integration of B cell responses through Toll-like receptors and antigen receptors" @default.
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