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• W1965749480 abstract "To assess the value of a single-phase dual-energy computed tomography (DECT) urography protocol with synchronous nephrographic-excretory phase enhancement and to calculate the potential dose reduction by omitting the unenhanced scan.Eighty-four patients referred for haematuria underwent CT urography using a protocol that included single-energy unenhanced and dual-energy contrast-enhanced with synchronous nephrographic-excretory phase scans. DECT-based images [virtual unenhanced (VUE), weighted average, and colour-coded iodine overlay] were reconstructed. Opacification degree by contrast media of the upper urinary tract, and image quality of virtual unenhanced images were independently evaluated using a four-point scale. The diagnostic accuracy in detecting urothelial tumours on DECT-based images was determined. The dose of a theoretical dual-phase single-energy protocol was obtained by multiplying the effective dose of the unenhanced single-energy acquisition by two. Radiation dose saving by omitting the unenhanced scan was calculated.The degree of opacification was scored as optimal or good in 86.9% of cases (k = 0.72); VUE image quality was excellent or good in 83.3% of cases (k = 0.82). Sensitivity, specificity, positive predictive value, and negative predictive value for urothelial tumours detection were 85.7, 98.6, 92.3, and 97.1%. Omission of the unenhanced scan led to a mean dose reduction of 42.7 ± 5%.Single-phase DECT urography with synchronous nephrographic-excretory phase enhancement represents an accurate all-in-one'' approach with a radiation dose saving up to 45% compared with a standard dual-phase protocol." @default.
• W1965749480 created "2016-06-24" @default.
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• W1965749480 date "2013-02-01" @default.
• W1965749480 modified "2023-09-24" @default.
• W1965749480 title "Single-phase dual-energy CT urography in the evaluation of haematuria" @default.
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• W1965749480 doi "https://doi.org/10.1016/j.crad.2012.11.001" @default.
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