FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965750971> ?p ?o ?g. }

• W1965750971 endingPage "19802" @default.
• W1965750971 startingPage "19797" @default.
• W1965750971 abstract "The Cse4p-containing centromere regions of Candida albicans have unique and different DNA sequences on each of the eight chromosomes. In a closely related yeast, C. dubliniensis , we have identified the centromeric histone, CdCse4p, and shown that it is localized at the kinetochore. We have identified putative centromeric regions, orthologous to the C. albicans centromeres, in each of the eight C. dubliniensis chromosomes by bioinformatic analysis. Chromatin immunoprecipitation followed by PCR using a specific set of primers confirmed that these regions bind CdCse4p in vivo . As in C. albicans , the CdCse4p-associated core centromeric regions are 3–5 kb in length and show no sequence similarity to one another. Comparative sequence analysis suggests that the Cse4p-rich centromere DNA sequences in these two species have diverged faster than other orthologous intergenic regions and even faster than our best estimated “neutral” mutation rate. However, the location of the centromere and the relative position of Cse4p-rich centromeric chromatin in the orthologous regions with respect to adjacent ORFs are conserved in both species, suggesting that centromere identity is not solely determined by DNA sequence. Unlike known point and regional centromeres of other organisms, centromeres in C. albicans and C. dubliniensis have no common centromere-specific sequence motifs or repeats except some of the chromosome-specific pericentric repeats that are found to be similar in these two species. We propose that centromeres of these two Candida species are of an intermediate type between point and regional centromeres." @default.
• W1965750971 created "2016-06-24" @default.
• W1965750971 creator A5013704488 @default.
• W1965750971 creator A5024921410 @default.
• W1965750971 creator A5033302091 @default.
• W1965750971 creator A5075228904 @default.
• W1965750971 date "2008-12-16" @default.
• W1965750971 modified "2023-10-02" @default.
• W1965750971 title "Rapid evolution of Cse4p-rich centromeric DNA sequences in closely related pathogenic yeasts, <i>Candida albicans</i> and <i>Candida dubliniensis</i>" @default.
• W1965750971 cites W1942775232 @default.
• W1965750971 cites W1982052327 @default.
• W1965750971 cites W1983642572 @default.
• W1965750971 cites W1986014242 @default.
• W1965750971 cites W2000242877 @default.
• W1965750971 cites W2010650285 @default.
• W1965750971 cites W2020599848 @default.
• W1965750971 cites W2020949713 @default.
• W1965750971 cites W2030474009 @default.
• W1965750971 cites W2031865039 @default.
• W1965750971 cites W2037607661 @default.
• W1965750971 cites W2038548564 @default.
• W1965750971 cites W2059694820 @default.
• W1965750971 cites W2061675425 @default.
• W1965750971 cites W2068481178 @default.
• W1965750971 cites W2068986932 @default.
• W1965750971 cites W2071941585 @default.
• W1965750971 cites W2082335793 @default.
• W1965750971 cites W2104481217 @default.
• W1965750971 cites W2105187962 @default.
• W1965750971 cites W2109372001 @default.
• W1965750971 cites W2118767738 @default.
• W1965750971 cites W2129296595 @default.
• W1965750971 cites W2130493916 @default.
• W1965750971 cites W2142144280 @default.
• W1965750971 cites W2144362290 @default.
• W1965750971 cites W2165268265 @default.
• W1965750971 cites W2165427373 @default.
• W1965750971 cites W2168582956 @default.
• W1965750971 cites W4239007372 @default.
• W1965750971 doi "https://doi.org/10.1073/pnas.0809770105" @default.
• W1965750971 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2604992" @default.
• W1965750971 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19060206" @default.
• W1965750971 hasPublicationYear "2008" @default.
• W1965750971 type Work @default.
• W1965750971 sameAs 1965750971 @default.
• W1965750971 citedByCount "76" @default.
• W1965750971 countsByYear W19657509712012 @default.
• W1965750971 countsByYear W19657509712013 @default.
• W1965750971 countsByYear W19657509712014 @default.
• W1965750971 countsByYear W19657509712015 @default.
• W1965750971 countsByYear W19657509712016 @default.
• W1965750971 countsByYear W19657509712017 @default.
• W1965750971 countsByYear W19657509712018 @default.
• W1965750971 countsByYear W19657509712019 @default.
• W1965750971 countsByYear W19657509712020 @default.
• W1965750971 countsByYear W19657509712021 @default.
• W1965750971 countsByYear W19657509712022 @default.
• W1965750971 countsByYear W19657509712023 @default.
• W1965750971 crossrefType "journal-article" @default.
• W1965750971 hasAuthorship W1965750971A5013704488 @default.
• W1965750971 hasAuthorship W1965750971A5024921410 @default.
• W1965750971 hasAuthorship W1965750971A5033302091 @default.
• W1965750971 hasAuthorship W1965750971A5075228904 @default.
• W1965750971 hasBestOaLocation W19657509711 @default.
• W1965750971 hasConcept C104317684 @default.
• W1965750971 hasConcept C145081991 @default.
• W1965750971 hasConcept C2776445003 @default.
• W1965750971 hasConcept C2780917455 @default.
• W1965750971 hasConcept C30481170 @default.
• W1965750971 hasConcept C54355233 @default.
• W1965750971 hasConcept C63491729 @default.
• W1965750971 hasConcept C86803240 @default.
• W1965750971 hasConceptScore W1965750971C104317684 @default.
• W1965750971 hasConceptScore W1965750971C145081991 @default.
• W1965750971 hasConceptScore W1965750971C2776445003 @default.
• W1965750971 hasConceptScore W1965750971C2780917455 @default.
• W1965750971 hasConceptScore W1965750971C30481170 @default.
• W1965750971 hasConceptScore W1965750971C54355233 @default.
• W1965750971 hasConceptScore W1965750971C63491729 @default.
• W1965750971 hasConceptScore W1965750971C86803240 @default.
• W1965750971 hasIssue "50" @default.
• W1965750971 hasLocation W19657509711 @default.
• W1965750971 hasLocation W19657509712 @default.
• W1965750971 hasLocation W19657509713 @default.
• W1965750971 hasLocation W19657509714 @default.
• W1965750971 hasOpenAccess W1965750971 @default.
• W1965750971 hasPrimaryLocation W19657509711 @default.
• W1965750971 hasRelatedWork W2028481852 @default.
• W1965750971 hasRelatedWork W2046593914 @default.
• W1965750971 hasRelatedWork W2062589993 @default.
• W1965750971 hasRelatedWork W2080367236 @default.
• W1965750971 hasRelatedWork W2117328946 @default.
• W1965750971 hasRelatedWork W2119855304 @default.
• W1965750971 hasRelatedWork W2139225413 @default.
• W1965750971 hasRelatedWork W2142056290 @default.
• W1965750971 hasRelatedWork W2145307402 @default.
• W1965750971 hasRelatedWork W606314263 @default.
• W1965750971 hasVolume "105" @default.

• next