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- W1965763721 startingPage "1479" @default.
- W1965763721 abstract "Phenylbutazone was administered to seven pairs of identical (monozygotic) twins and to seven pairs of fraternal (dizygotic) twins. Individual half-lives ranged from 1.2 to 7.3 days. Subjects with identical genotypes (monozygotic twins) exhibited very similar phenylbutazone half-lives; significantly greater differences in half-life occurred in dizygotic twins. The previously established large variations among individuals in phenylbutazone metabolism appear to be genetically, rather than environmentally, determined." @default.
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- W1965763721 date "1968-03-29" @default.
- W1965763721 modified "2023-10-09" @default.
- W1965763721 title "Genetic Control of Drug Levels in Man: Phenylbutazone" @default.
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- W1965763721 doi "https://doi.org/10.1126/science.159.3822.1479" @default.
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