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• W1965779683 abstract "Purpose.: Glaucoma may involve disturbances in retinal oxygenation and blood flow. The purpose of this study was to measure the effect of glaucoma filtration surgery on retinal vessel oxygen saturation. Methods.: A noninvasive spectrophotometric retinal oximeter was used to measure hemoglobin oxygen saturation in retinal arterioles and venules before and after glaucoma filtration surgery. Twenty-five consecutive patients were recruited, and 19 had adequate image quality. Fourteen underwent trabeculectomy and five glaucoma tube surgery. Twelve had primary open-angle glaucoma and seven had exfoliative glaucoma. IOP decreased from 23 ± 7 to 10 ± 4 mm Hg (mean ± SD, P = 0.0001). Results.: Oxygen saturation increased in retinal arterioles from 97% ± 4% to 99% ± 6% (n = 19; P = 0.046) after surgery and was unchanged in venules (63% ± 5% before surgery and 64% ± 6% after, P = 0.76). There were no significant changes in saturation in the fellow eyes (P > 0.60). The arteriovenous difference was 34% before and 36% after surgery (P = 0.35). Conclusions.: Glaucoma filtration surgery had almost no effect on retinal vessel oxygen saturation." @default.
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• W1965779683 date "2009-11-01" @default.
• W1965779683 modified "2023-10-04" @default.
• W1965779683 title "Glaucoma Filtration Surgery and Retinal Oxygen Saturation" @default.
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• W1965779683 doi "https://doi.org/10.1167/iovs.08-3117" @default.
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