FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965807459> ?p ?o ?g. }

• W1965807459 endingPage "409" @default.
• W1965807459 startingPage "405" @default.
• W1965807459 abstract "To clarify the role of anticoagulation with heparin and protamine reversal on the effectiveness of heparin bonding or coating of pulmonary artery catheters in preventing thrombus formation in the Rhesus monkey.A controlled, unblinded, open-labeled study.A research laboratory at Tulane School of Medicine (New Orleans, LA).Twenty-four anesthetized Rhesus monkeys.The monkeys were assigned to one of four groups. In the first group (group A), non-heparin-coated catheters were inserted into a femoral vein through an incision, advanced proximally for a distance of 30 cm, and left in place for 1 hour. In the second group (group B), heparin-coated catheters were placed and evaluated in the same manner as in group A. In the third group (group C), the primates received 3 mg/kg of heparin intravenously (i.v.) before insertion of a non-heparin-coated pulmonary artery catheter. After the catheter had been in place for 1 hour, protamine, 3 mg/kg i.v., was administered, and the catheter was left in place for an additional hour. In the final group (group D), the primates received 3 mg/kg of heparin i.v. before insertion of a heparin-coated pulmonary artery catheter. After the catheter had been in place for 1 hour, protamine, 3 mg/kg i.v., was administered, and the catheter was left in place for an additional hour. In each group, the catheter was withdrawn with the balloon inflated to minimize any stripping of thrombus from the surface of the catheter. Thrombus was removed from the catheter through a femoral vein cutdown and weighed. Laboratory values were determined for each animal, and clot formation was evaluated in each group. After completion of the study, the animals were returned to the primate breeding colony.There were no significant differences in hematocrit, prothrombin time, partial thromboplastin time, or platelet levels among the four groups; therefore, the data were pooled. Clots were observed on five of six catheters in both groups A and C; however, clot formation was seen in one of six catheters in group B and three of six catheters in group D. There was a statistically significant difference (p < 0.01) in mean clot weight in group A (265 +/- 68 mg; range, 0 to 447 mg) compared with 13 +/- 13 mg in group B (range, 0 to 80 mg). There was no significant difference in mean clot weight in group C (104 +/- 35 mg; range, 0 to 202 mg) compared with group D (24 +/- 16 mg, range, 0 to 98 mg). Additionally, in group C, the mean clot weight was significantly less than in group A.Anticoagulation of primates with heparin before catheter insertion imparts some protection to non-coated catheters, and protamine reversal of anticoagulation with heparin may partially negate the protective effect seen with heparin-coated pulmonary artery catheters." @default.
• W1965807459 created "2016-06-24" @default.
• W1965807459 creator A5018558604 @default.
• W1965807459 creator A5060383122 @default.
• W1965807459 creator A5066047527 @default.
• W1965807459 date "1999-08-01" @default.
• W1965807459 modified "2023-09-23" @default.
• W1965807459 title "Do anticoagulation with heparin and protamine reversal alter thrombogenicity of coated and noncoated pulmonary artery catheters?" @default.
• W1965807459 cites W107640453 @default.
• W1965807459 cites W131193627 @default.
• W1965807459 cites W1963758619 @default.
• W1965807459 cites W1968823926 @default.
• W1965807459 cites W197392028 @default.
• W1965807459 cites W1974484017 @default.
• W1965807459 cites W1985113685 @default.
• W1965807459 cites W1990494533 @default.
• W1965807459 cites W1997352113 @default.
• W1965807459 cites W1998033561 @default.
• W1965807459 cites W1998142102 @default.
• W1965807459 cites W2002604381 @default.
• W1965807459 cites W2002934391 @default.
• W1965807459 cites W2004736807 @default.
• W1965807459 cites W2007033435 @default.
• W1965807459 cites W2009349445 @default.
• W1965807459 cites W2013592370 @default.
• W1965807459 cites W2017483648 @default.
• W1965807459 cites W2024114674 @default.
• W1965807459 cites W2024641990 @default.
• W1965807459 cites W2035276023 @default.
• W1965807459 cites W2039591764 @default.
• W1965807459 cites W2051344829 @default.
• W1965807459 cites W2062839391 @default.
• W1965807459 cites W2067215489 @default.
• W1965807459 cites W2074299379 @default.
• W1965807459 cites W2076109071 @default.
• W1965807459 cites W2077073832 @default.
• W1965807459 cites W2080682567 @default.
• W1965807459 cites W2081610840 @default.
• W1965807459 cites W2093604095 @default.
• W1965807459 cites W2093821740 @default.
• W1965807459 cites W2137051362 @default.
• W1965807459 cites W2137734322 @default.
• W1965807459 cites W2137994341 @default.
• W1965807459 cites W2150256483 @default.
• W1965807459 cites W2155600196 @default.
• W1965807459 cites W2332898214 @default.
• W1965807459 cites W2340468754 @default.
• W1965807459 cites W2406171144 @default.
• W1965807459 cites W2407348763 @default.
• W1965807459 cites W2408971219 @default.
• W1965807459 cites W2411471380 @default.
• W1965807459 cites W2413300648 @default.
• W1965807459 cites W2417026009 @default.
• W1965807459 cites W2461408713 @default.
• W1965807459 cites W2461613575 @default.
• W1965807459 cites W2798643531 @default.
• W1965807459 cites W62537 @default.
• W1965807459 cites W2017521463 @default.
• W1965807459 doi "https://doi.org/10.1016/s1053-0770(99)90211-2" @default.
• W1965807459 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10468252" @default.
• W1965807459 hasPublicationYear "1999" @default.
• W1965807459 type Work @default.
• W1965807459 sameAs 1965807459 @default.
• W1965807459 citedByCount "5" @default.
• W1965807459 crossrefType "journal-article" @default.
• W1965807459 hasAuthorship W1965807459A5018558604 @default.
• W1965807459 hasAuthorship W1965807459A5060383122 @default.
• W1965807459 hasAuthorship W1965807459A5066047527 @default.
• W1965807459 hasConcept C141071460 @default.
• W1965807459 hasConcept C2776649359 @default.
• W1965807459 hasConcept C2776820930 @default.
• W1965807459 hasConcept C2777557582 @default.
• W1965807459 hasConcept C2777987278 @default.
• W1965807459 hasConcept C2779723990 @default.
• W1965807459 hasConcept C2780835560 @default.
• W1965807459 hasConcept C2780868729 @default.
• W1965807459 hasConcept C2780940725 @default.
• W1965807459 hasConcept C2781267111 @default.
• W1965807459 hasConcept C2781362458 @default.
• W1965807459 hasConcept C42219234 @default.
• W1965807459 hasConcept C71924100 @default.
• W1965807459 hasConceptScore W1965807459C141071460 @default.
• W1965807459 hasConceptScore W1965807459C2776649359 @default.
• W1965807459 hasConceptScore W1965807459C2776820930 @default.
• W1965807459 hasConceptScore W1965807459C2777557582 @default.
• W1965807459 hasConceptScore W1965807459C2777987278 @default.
• W1965807459 hasConceptScore W1965807459C2779723990 @default.
• W1965807459 hasConceptScore W1965807459C2780835560 @default.
• W1965807459 hasConceptScore W1965807459C2780868729 @default.
• W1965807459 hasConceptScore W1965807459C2780940725 @default.
• W1965807459 hasConceptScore W1965807459C2781267111 @default.
• W1965807459 hasConceptScore W1965807459C2781362458 @default.
• W1965807459 hasConceptScore W1965807459C42219234 @default.
• W1965807459 hasConceptScore W1965807459C71924100 @default.
• W1965807459 hasIssue "4" @default.
• W1965807459 hasLocation W19658074591 @default.
• W1965807459 hasLocation W19658074592 @default.
• W1965807459 hasOpenAccess W1965807459 @default.

• next