FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965869420> ?p ?o ?g. }

• W1965869420 endingPage "573" @default.
• W1965869420 startingPage "567" @default.
• W1965869420 abstract "Abstract: The rates of the phosphorylation and dephosphorylation of 2-deoxyglucose were measured in rat brain in vivo using tracer kinetic techniques. The rate constant for each reaction was estimated from two separate experiments with different protocols for tracer administration. Tracer amounts of [1-14C]2-deoxyglucose (1 μCi) were injected through the internal carotid artery (intraarterial experiment), or through the atrium (intravenous experiment). Brains were sampled by freeze-blowing at various times after the injection. In the intraarterial experiment, the rate constant for the forward reaction from 2-deoxyglucose to 2-deoxyglucose phosphate was calculated by dividing the initial rate of 2-deoxyglucose phosphate production by the 2-deoxyglucose content in brain. The rate constant for the reverse reaction from 2-deoxyyglucose phosphate to 2-deoxyglucose was calculated from the decay constant of 2-deoxyglucose phosphate. The rate constants estimated were 10.1 ± 1.4%/min (SD) and 3.00 ± 0.01%/min (SD), respectively, for the forward and reverse reactions. In the intravenous experiment, rate constants for both reactions were estimated by compartmental analysis. By fitting data to program SAAM-27, the rate constants for the forward and reverse reactions were estimated as 11.4 ± 0.4%/min (SD) and 5.1 ± 0.4%/min (SD), respectively. The rate constants determined were compared to those for the reactions between glucose and glucose-6-phosphate, estimated previously from labeled glucoses. It is concluded that the rate of glucose utilization measured by the 2-deoxyglucose method reflects the rate of the hexokinase reaction and not the rate of glucose utilization or brain energy utilization." @default.
• W1965869420 created "2016-06-24" @default.
• W1965869420 creator A5004652247 @default.
• W1965869420 creator A5062776702 @default.
• W1965869420 date "1985-02-01" @default.
• W1965869420 modified "2023-09-26" @default.
• W1965869420 title "Metabolic Fluxes Between [¹⁴C]2-Deoxy-D-Glucose and [¹⁴C]2-Deoxy-D-Glucose-6-Phosphate in Brain In Vivo" @default.
• W1965869420 cites W1486708736 @default.
• W1965869420 cites W1492843876 @default.
• W1965869420 cites W1546192695 @default.
• W1965869420 cites W1565787013 @default.
• W1965869420 cites W186464998 @default.
• W1965869420 cites W1964664628 @default.
• W1965869420 cites W1998834237 @default.
• W1965869420 cites W2007856779 @default.
• W1965869420 cites W2020950334 @default.
• W1965869420 cites W2031565400 @default.
• W1965869420 cites W2035183926 @default.
• W1965869420 cites W2048307995 @default.
• W1965869420 cites W2090203522 @default.
• W1965869420 cites W2090306035 @default.
• W1965869420 cites W2146250938 @default.
• W1965869420 cites W2397861637 @default.
• W1965869420 cites W92757606 @default.
• W1965869420 doi "https://doi.org/10.1111/j.1471-4159.1985.tb05450.x" @default.
• W1965869420 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3965622" @default.
• W1965869420 hasPublicationYear "1985" @default.
• W1965869420 type Work @default.
• W1965869420 sameAs 1965869420 @default.
• W1965869420 citedByCount "51" @default.
• W1965869420 countsByYear W19658694202013 @default.
• W1965869420 countsByYear W19658694202014 @default.
• W1965869420 countsByYear W19658694202016 @default.
• W1965869420 countsByYear W19658694202017 @default.
• W1965869420 countsByYear W19658694202018 @default.
• W1965869420 countsByYear W19658694202019 @default.
• W1965869420 countsByYear W19658694202020 @default.
• W1965869420 countsByYear W19658694202021 @default.
• W1965869420 countsByYear W19658694202022 @default.
• W1965869420 crossrefType "journal-article" @default.
• W1965869420 hasAuthorship W1965869420A5004652247 @default.
• W1965869420 hasAuthorship W1965869420A5062776702 @default.
• W1965869420 hasConcept C112705442 @default.
• W1965869420 hasConcept C121332964 @default.
• W1965869420 hasConcept C126322002 @default.
• W1965869420 hasConcept C139254425 @default.
• W1965869420 hasConcept C148898269 @default.
• W1965869420 hasConcept C150903083 @default.
• W1965869420 hasConcept C161790260 @default.
• W1965869420 hasConcept C175113610 @default.
• W1965869420 hasConcept C177322064 @default.
• W1965869420 hasConcept C181199279 @default.
• W1965869420 hasConcept C185592680 @default.
• W1965869420 hasConcept C192670549 @default.
• W1965869420 hasConcept C20251656 @default.
• W1965869420 hasConcept C207001950 @default.
• W1965869420 hasConcept C2777132085 @default.
• W1965869420 hasConcept C2777790778 @default.
• W1965869420 hasConcept C2779826832 @default.
• W1965869420 hasConcept C2780909259 @default.
• W1965869420 hasConcept C55493867 @default.
• W1965869420 hasConcept C62231903 @default.
• W1965869420 hasConcept C62520636 @default.
• W1965869420 hasConcept C71924100 @default.
• W1965869420 hasConcept C86803240 @default.
• W1965869420 hasConcept C93391505 @default.
• W1965869420 hasConceptScore W1965869420C112705442 @default.
• W1965869420 hasConceptScore W1965869420C121332964 @default.
• W1965869420 hasConceptScore W1965869420C126322002 @default.
• W1965869420 hasConceptScore W1965869420C139254425 @default.
• W1965869420 hasConceptScore W1965869420C148898269 @default.
• W1965869420 hasConceptScore W1965869420C150903083 @default.
• W1965869420 hasConceptScore W1965869420C161790260 @default.
• W1965869420 hasConceptScore W1965869420C175113610 @default.
• W1965869420 hasConceptScore W1965869420C177322064 @default.
• W1965869420 hasConceptScore W1965869420C181199279 @default.
• W1965869420 hasConceptScore W1965869420C185592680 @default.
• W1965869420 hasConceptScore W1965869420C192670549 @default.
• W1965869420 hasConceptScore W1965869420C20251656 @default.
• W1965869420 hasConceptScore W1965869420C207001950 @default.
• W1965869420 hasConceptScore W1965869420C2777132085 @default.
• W1965869420 hasConceptScore W1965869420C2777790778 @default.
• W1965869420 hasConceptScore W1965869420C2779826832 @default.
• W1965869420 hasConceptScore W1965869420C2780909259 @default.
• W1965869420 hasConceptScore W1965869420C55493867 @default.
• W1965869420 hasConceptScore W1965869420C62231903 @default.
• W1965869420 hasConceptScore W1965869420C62520636 @default.
• W1965869420 hasConceptScore W1965869420C71924100 @default.
• W1965869420 hasConceptScore W1965869420C86803240 @default.
• W1965869420 hasConceptScore W1965869420C93391505 @default.
• W1965869420 hasIssue "2" @default.
• W1965869420 hasLocation W19658694201 @default.
• W1965869420 hasLocation W19658694202 @default.
• W1965869420 hasOpenAccess W1965869420 @default.
• W1965869420 hasPrimaryLocation W19658694201 @default.
• W1965869420 hasRelatedWork W1542211599 @default.
• W1965869420 hasRelatedWork W1884432119 @default.
• W1965869420 hasRelatedWork W1965869420 @default.

• next