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- W1965892995 abstract "An in vitro peripheral lymphocyte blastogenesis system was used to investigate the biological activities of the fungal toxin fusarochromanone (TDP-1) and its monoacetyl derivative TDP-2. Briefly, cultures of human or bovine peripheral lymphocytes were exposed to TDP-1 or TDP-2 and a mitogen (PHA, Con A or PWM). After a standard incubation time, cell proliferation was quantified using the MTT bioassay. Human and bovine lymphocyte proliferation was inhibited by high concentrations of TDP-1; however, bovine lymphocyte proliferation was significantly increased at low concentrations of TDP-1. TDP-2 has similar but less pronounced effects on lymphocyte proliferation." @default.
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- W1965892995 date "1992-01-01" @default.
- W1965892995 modified "2023-09-25" @default.
- W1965892995 title "Immunomodulatory effects of fusarochromanones TDP-1 and TDP-2" @default.
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- W1965892995 doi "https://doi.org/10.1002/nt.2620010105" @default.
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