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• W1965908219 startingPage "372" @default.
• W1965908219 abstract "Cigarette smoking is an important risk factor for gastrointestinal (GI) disorders, including peptic ulcers, inflammatory bowel diseases, such as Crohn's disease and cancer. In this review, the relationship between smoking and GI disorders and the underlying mechanisms are discussed. It has been demonstrated that cigarette smoking is positively associated with the pathogenesis of peptic ulcers and the delay of ulcer healing. Mechanistic studies have shown that cigarette smoke and its active ingredients can cause mucosal cell death, inhibit cell renewal, decrease blood flow in the GI mucosa and interfere with the mucosal immune system. Cigarette smoking is also an independent risk factor for various types of cancer of the GI tract. In this review, we also summarize the mechanisms through which cigarette smoking induces tumorigenesis and promotes the development of cancer in various sections of the GI tract. These mechanisms include the activation of nicotinic acetylcholine receptors, the formation of DNA adducts, the stimulation of tumor angiogenesis and the modulation of immune responses in the GI mucosa. A full understanding of these pathogenic mechanisms may help us to develop more effective therapies for GI disorders in the future." @default.
• W1965908219 created "2016-06-24" @default.
• W1965908219 creator A5030112054 @default.
• W1965908219 creator A5044119010 @default.
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• W1965908219 creator A5066803805 @default.
• W1965908219 creator A5087047235 @default.
• W1965908219 creator A5091398589 @default.
• W1965908219 date "2014-05-22" @default.
• W1965908219 modified "2023-10-06" @default.
• W1965908219 title "Cigarette smoking and gastrointestinal diseases: The causal relationship and underlying molecular mechanisms (Review)" @default.
• W1965908219 cites W1534160452 @default.
• W1965908219 cites W1566435523 @default.
• W1965908219 cites W1577251139 @default.
• W1965908219 cites W1607968733 @default.
• W1965908219 cites W1778572461 @default.
• W1965908219 cites W1964952541 @default.
• W1965908219 cites W1966064580 @default.
• W1965908219 cites W1966079163 @default.
• W1965908219 cites W1966990785 @default.
• W1965908219 cites W1973297253 @default.
• W1965908219 cites W1976857316 @default.
• W1965908219 cites W1980740938 @default.
• W1965908219 cites W1982153589 @default.
• W1965908219 cites W1983241056 @default.
• W1965908219 cites W1985012719 @default.
• W1965908219 cites W1987070557 @default.
• W1965908219 cites W1991806827 @default.
• W1965908219 cites W1993544268 @default.
• W1965908219 cites W1997828131 @default.
• W1965908219 cites W2001582253 @default.
• W1965908219 cites W2004710474 @default.
• W1965908219 cites W2007164294 @default.
• W1965908219 cites W2007212877 @default.
• W1965908219 cites W2007258605 @default.
• W1965908219 cites W2007606465 @default.
• W1965908219 cites W2010665791 @default.
• W1965908219 cites W2010668503 @default.
• W1965908219 cites W2012315119 @default.
• W1965908219 cites W2021656312 @default.
• W1965908219 cites W2022669416 @default.
• W1965908219 cites W2024529818 @default.
• W1965908219 cites W2025977764 @default.
• W1965908219 cites W2029367212 @default.
• W1965908219 cites W2029434100 @default.
• W1965908219 cites W2031606495 @default.
• W1965908219 cites W2032999541 @default.
• W1965908219 cites W2035104435 @default.
• W1965908219 cites W2035143315 @default.
• W1965908219 cites W2038819848 @default.
• W1965908219 cites W2041435471 @default.
• W1965908219 cites W2041800958 @default.
• W1965908219 cites W2046780536 @default.
• W1965908219 cites W2046812765 @default.
• W1965908219 cites W2048375090 @default.
• W1965908219 cites W2048400867 @default.
• W1965908219 cites W2050516456 @default.
• W1965908219 cites W2050820138 @default.
• W1965908219 cites W2051607934 @default.
• W1965908219 cites W2055201543 @default.
• W1965908219 cites W2056666823 @default.
• W1965908219 cites W2057968053 @default.
• W1965908219 cites W2059196429 @default.
• W1965908219 cites W2062742701 @default.
• W1965908219 cites W2068300145 @default.
• W1965908219 cites W2068461425 @default.
• W1965908219 cites W2069535648 @default.
• W1965908219 cites W2070804006 @default.
• W1965908219 cites W2071229743 @default.
• W1965908219 cites W2077312106 @default.
• W1965908219 cites W2080222605 @default.
• W1965908219 cites W2084150021 @default.
• W1965908219 cites W2086953574 @default.
• W1965908219 cites W2089220441 @default.
• W1965908219 cites W2095436745 @default.
• W1965908219 cites W2099444176 @default.
• W1965908219 cites W2102144390 @default.
• W1965908219 cites W2102517990 @default.
• W1965908219 cites W2106758749 @default.
• W1965908219 cites W2118278569 @default.
• W1965908219 cites W2120143163 @default.
• W1965908219 cites W2120929800 @default.
• W1965908219 cites W2123105952 @default.
• W1965908219 cites W2124567477 @default.
• W1965908219 cites W2125252926 @default.
• W1965908219 cites W2127106146 @default.
• W1965908219 cites W2128448728 @default.
• W1965908219 cites W2130373865 @default.
• W1965908219 cites W2131480678 @default.
• W1965908219 cites W2132253885 @default.
• W1965908219 cites W2137570167 @default.
• W1965908219 cites W2147765338 @default.
• W1965908219 cites W2151701525 @default.
• W1965908219 cites W2151942048 @default.

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