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• W1965911389 endingPage "2032" @default.
• W1965911389 startingPage "2024" @default.
• W1965911389 abstract "Fermentation properties of oligosaccharides derived from lactulose (OsLu) and lactose (GOS) have been assessed in pH-controlled anaerobic batch cultures using lactulose and Vivinal-GOS as reference carbohydrates. Changes in gut bacterial populations and their metabolic activities were monitored over 24 h by fluorescent in situ hybridization (FISH) and by measurement of short-chain fatty acid (SCFA) production. Lactulose-derived oligosaccharides were selectively fermented by Bifidobacterium and lactic acid bacterial populations producing higher SCFA concentrations compared to GOS. The highest total SCFA production was from Vivinal-GOS > lactulose > OsLu > GOS. Longer incubation periods produced a selective fermentation of OsLu when they were used as a carbon source reaching the highest selective index scores. The new oligosaccharides may constitute a good alternative to lactulose, and they could belong to a new generation of prebiotics to be used as a functional ingredient for improving the composition of gut microflora." @default.
• W1965911389 created "2016-06-24" @default.
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• W1965911389 date "2012-02-15" @default.
• W1965911389 modified "2023-10-17" @default.
• W1965911389 title "In Vitro Fermentation of Lactulose-Derived Oligosaccharides by Mixed Fecal Microbiota" @default.
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• W1965911389 doi "https://doi.org/10.1021/jf203622d" @default.
• W1965911389 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22292561" @default.
• W1965911389 hasPublicationYear "2012" @default.
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