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- W1965920271 abstract "The gene product of the nef gene of HIV-1 acts both to increase the infectivity of viral particles and to reduce the expression of the CD4 receptor molecule on the cell surface. These two functions of Nef may be related, in that downregulation of CD4 may promote the production of HIV that has greater infectivity." @default.
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- W1965920271 date "1994-08-01" @default.
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- W1965920271 title "The HIV-1 nef gene acts as a positive viral infectivity factor" @default.
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- W1965920271 doi "https://doi.org/10.1016/0966-842x(94)90007-8" @default.
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