FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1965975087> ?p ?o ?g. }

• W1965975087 endingPage "917" @default.
• W1965975087 startingPage "911" @default.
• W1965975087 abstract "Background: Prophylactic central neck dissection (CND) has been proposed in the treatment of patients affected by papillary thyroid carcinoma (PTC) with clinically negative neck lymph nodes. The procedure allows pathologic staging of lymph nodes of the central compartment and treatment of the micrometastases. Nevertheless, the morbidity that its routine use adds to the total thyroidectomy must be taken into account. The aim of this study was to characterize the morbidity that CND adds to the total thyroidectomy. Methods: This was a retrospective study of 1087 patients with PTC and clinically negative neck lymph nodes. Patients were divided into three study groups: Group A, total thyroidectomy; Group B, total thyroidectomy and ipsilateral CND; Group C, total thyroidectomy and bilateral CND. Primary endpoints of the study were evaluated by comparing the rates of transient and permanent recurrent laryngeal nerve (RLN) injury and hypoparathyroidism in the three study groups. Results: Analysis of data showed no significant differences in the rate of transient (Group A: 3.6%, Group B: 3.9%, and Group C: 5.5%; p=0.404) and permanent (Group A: 1%, Group B: 0.5%, and Group C: 2.3%; p=0.099) RLN injury between the three study groups. Both ipsilateral CND and bilateral CND were associated with a higher rate of transient hypoparathyroidism (Group: A 27.7%, Group B: 36.1%, and Group C: 51.9%; p=0.014; odds ratio [OR]: 1.477; 95% confidence interval [CI]: 1.091–2.001; p<0.001; OR: 2.827; 95% CI: 2.065–3.870, respectively). Bilateral CND had a higher rate of permanent hypoparathyroidism (Group A: 6.3%, Group B: 7%, and Group C: 16.2%; p<0.001; OR: 2.860; 95% CI: 1.725–4.743). Conclusions: The increased rates of transient and permanent hypoparathyroidism in our series suggest a critical review of indications for the routine use of prophylactic CND for PTC. Prophylactic CND ipsilateral to the tumor associated with total thyroidectomy may represent an effective strategy for reducing the rate of permanent hypoparathyroidism. Concomitant completion contralateral paratracheal lymph node neck dissection should be performed in presence of lymph node metastasis on intraoperative frozen-section pathology. This approach limits the use of bilateral CND to patients with intraoperative pathological findings of lymph node metastases." @default.
• W1965975087 created "2016-06-24" @default.
• W1965975087 creator A5001843029 @default.
• W1965975087 creator A5015981592 @default.
• W1965975087 creator A5033904860 @default.
• W1965975087 creator A5038703328 @default.
• W1965975087 creator A5040907908 @default.
• W1965975087 creator A5053481729 @default.
• W1965975087 creator A5086966384 @default.
• W1965975087 date "2012-09-01" @default.
• W1965975087 modified "2023-09-30" @default.
• W1965975087 title "Complications of Central Neck Dissection in Patients with Papillary Thyroid Carcinoma: Results of a Study on 1087 Patients and Review of the Literature" @default.
• W1965975087 cites W1574663596 @default.
• W1965975087 cites W1964644395 @default.
• W1965975087 cites W1965477889 @default.
• W1965975087 cites W1969575697 @default.
• W1965975087 cites W1972284299 @default.
• W1965975087 cites W1979299167 @default.
• W1965975087 cites W1979627465 @default.
• W1965975087 cites W1982712592 @default.
• W1965975087 cites W1988598180 @default.
• W1965975087 cites W1996429081 @default.
• W1965975087 cites W2002000696 @default.
• W1965975087 cites W2002484504 @default.
• W1965975087 cites W2008311948 @default.
• W1965975087 cites W2013947842 @default.
• W1965975087 cites W2016336194 @default.
• W1965975087 cites W2017242914 @default.
• W1965975087 cites W2019368784 @default.
• W1965975087 cites W2022911526 @default.
• W1965975087 cites W2026580668 @default.
• W1965975087 cites W2039504315 @default.
• W1965975087 cites W2045344651 @default.
• W1965975087 cites W2057183818 @default.
• W1965975087 cites W2058875076 @default.
• W1965975087 cites W2062963159 @default.
• W1965975087 cites W2074628312 @default.
• W1965975087 cites W2080240500 @default.
• W1965975087 cites W2081148836 @default.
• W1965975087 cites W2082067526 @default.
• W1965975087 cites W2082260444 @default.
• W1965975087 cites W2086260297 @default.
• W1965975087 cites W2086851340 @default.
• W1965975087 cites W2102269711 @default.
• W1965975087 cites W2104147599 @default.
• W1965975087 cites W2107395330 @default.
• W1965975087 cites W2116542352 @default.
• W1965975087 cites W2123353245 @default.
• W1965975087 cites W2141353927 @default.
• W1965975087 cites W2147920204 @default.
• W1965975087 cites W2158730241 @default.
• W1965975087 cites W2163175491 @default.
• W1965975087 cites W2316678488 @default.
• W1965975087 cites W4254971556 @default.
• W1965975087 doi "https://doi.org/10.1089/thy.2012.0011" @default.
• W1965975087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22827494" @default.
• W1965975087 hasPublicationYear "2012" @default.
• W1965975087 type Work @default.
• W1965975087 sameAs 1965975087 @default.
• W1965975087 citedByCount "312" @default.
• W1965975087 countsByYear W19659750872012 @default.
• W1965975087 countsByYear W19659750872013 @default.
• W1965975087 countsByYear W19659750872014 @default.
• W1965975087 countsByYear W19659750872015 @default.
• W1965975087 countsByYear W19659750872016 @default.
• W1965975087 countsByYear W19659750872017 @default.
• W1965975087 countsByYear W19659750872018 @default.
• W1965975087 countsByYear W19659750872019 @default.
• W1965975087 countsByYear W19659750872020 @default.
• W1965975087 countsByYear W19659750872021 @default.
• W1965975087 countsByYear W19659750872022 @default.
• W1965975087 countsByYear W19659750872023 @default.
• W1965975087 crossrefType "journal-article" @default.
• W1965975087 hasAuthorship W1965975087A5001843029 @default.
• W1965975087 hasAuthorship W1965975087A5015981592 @default.
• W1965975087 hasAuthorship W1965975087A5033904860 @default.
• W1965975087 hasAuthorship W1965975087A5038703328 @default.
• W1965975087 hasAuthorship W1965975087A5040907908 @default.
• W1965975087 hasAuthorship W1965975087A5053481729 @default.
• W1965975087 hasAuthorship W1965975087A5086966384 @default.
• W1965975087 hasConcept C121608353 @default.
• W1965975087 hasConcept C126322002 @default.
• W1965975087 hasConcept C141071460 @default.
• W1965975087 hasConcept C142724271 @default.
• W1965975087 hasConcept C156957248 @default.
• W1965975087 hasConcept C167135981 @default.
• W1965975087 hasConcept C2775862295 @default.
• W1965975087 hasConcept C2775941721 @default.
• W1965975087 hasConcept C2777074255 @default.
• W1965975087 hasConcept C2777546739 @default.
• W1965975087 hasConcept C2778474501 @default.
• W1965975087 hasConcept C2779720271 @default.
• W1965975087 hasConcept C2779761222 @default.
• W1965975087 hasConcept C2780824555 @default.
• W1965975087 hasConcept C2993294228 @default.
• W1965975087 hasConcept C44249647 @default.
• W1965975087 hasConcept C526584372 @default.
• W1965975087 hasConcept C71924100 @default.

• next