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• W1966000966 abstract "You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Quality of Life1 Apr 2011634 DEVELOPMENT OF A DISEASE-SPECIFIC INSTRUMENT TO MEASURE STONE FORMERS' HEALTH-RELATED QUALITY OF LIFE Kristina L. Penniston and Stephen Y. Nakada Kristina L. PennistonKristina L. Penniston Madison, WI More articles by this author and Stephen Y. NakadaStephen Y. Nakada Madison, WI More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2011.02.1510AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Urolithiasis is associated with pain and other health-related quality of life (QOL) decrements. Yet, despite this, no urolithiasis-specific instrument with which to measure patients' QOL exists. QOL is an appropriate and important endpoint in urolithiasis. We developed the Wisconsin StoneQOL, a disease-specific instrument to assess the QOL of patients with urolithiasis. METHODS Patients and urology providers identified important concepts in focus groups and cognitive interviews. Patients (n=34) were largely recurrent calcium stone formers (M:F, 1.5; 50 ± 3.2 y); all were considered stable with respect to their stone disease. A preliminary instrument was created with 65 topics. Patients provided feedback about the frequency and importance of each item, allowing for item reduction and further refinement of the instrument. A 32-question instrument, using a Likert scale similar to other QOL and psychometric instruments, was drafted based on calculated impact factors of the preliminary tool. 100 patients from our clinic participated in testing, which allowed us to assess the instrument's internal consistency, reliability, respondent burden, and ability to detect change. RESULTS Salient issues related to urolithiasis symptoms and effects on patients' QOL were identified and formulated into a 2-page survey. Respondent burden is acceptable. Internal consistency of the instrument is high (Cronbach's α-coefficients >0.86 for all domains). Preliminary testing differentiates between acute vs. stable stone disease with lower QOL scores associated with disease exacerbation (p<0.0001 for total instrument score). Principal components analysis suggests further refinement of the instrument is possible. Testing of the instrument's discriminant and concurrent validity are ongoing. CONCLUSIONS The Wisconsin StoneQOL holds promise, based on analysis of face validity and internal consistency, as a disease-specific instrument that captures the unique symptoms and challenges associated with urolithiasis and which is capable of assessing the health-related QOL of stone formers at various points along their disease continuum. © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4SApril 2011Page: e256 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.Metrics Author Information Kristina L. Penniston Madison, WI More articles by this author Stephen Y. Nakada Madison, WI More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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• W1966000966 title "634 DEVELOPMENT OF A DISEASE-SPECIFIC INSTRUMENT TO MEASURE STONE FORMERS' HEALTH-RELATED QUALITY OF LIFE" @default.
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