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- W1966003082 abstract "An ultra-reliable technique for detecting trace quantities of biomolecules is reported. The technique called “co-detection” exploits the non-linear redundancy amongst synthetically patterned biomolecular logic circuits for deciphering the presence or absence of target biomolecules in a sample. In this paper, we verify the “co-detection” principle on gold-nanoparticle-based conductimetric soft-logic circuits which use a silver-enhancement technique for signal amplification. Using co-detection, we have been able to demonstrate a great improvement in the reliability of detecting mouse IgG at concentration levels that are 105 lower than the concentration of rabbit IgG which serves as background interference." @default.
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- W1966003082 date "2010-11-15" @default.
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- W1966003082 title "Co-detection: Ultra-reliable nanoparticle-based electrical detection of biomolecules in the presence of large background interference" @default.
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- W1966003082 doi "https://doi.org/10.1016/j.bios.2010.08.067" @default.
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