FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966014546> ?p ?o ?g. }

• W1966014546 endingPage "544" @default.
• W1966014546 startingPage "537" @default.
• W1966014546 abstract "gamma-Hydroxybutyric acid (GHB), an endogenous organic acid catabolite of gamma-aminobutyric acid (GABA), has been shown to have tissue-protective effects in various organs, including the brain. We examined the potential neuroprotective effect of GHB and its chemical precursors, gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD), in the rodent ischemic stroke model by intraluminal filament middle cerebral artery occlusion (MCAO). Adult male Sprague-Dawley rats underwent transient left-sided MCAO and received intraperitoneal treatment with 300 mg/kg of GHB, GBL, 1,4-BD, or control vehicle given at 30 min before, as well as 180 and 360 min after the onset of ischemia. Infarct volumes were determined 24 h after MCAO. In transient MCAO, the mean volume of infarction for control rats was 464.4 +/- 17.9 cu.mm versus 273.6 +/- 53.1, 233.3 +/- 44.7, and 275.4 +/- 39.9 cu.mm for rats treated with 1,4-BD (P < 0.05), GBL (P < 0.05), and GHB (P < 0.05), respectively. We conclude that GHB, GBL, and 1,4-BD protect against rat focal cerebral ischemia from transient MCAO." @default.
• W1966014546 created "2016-06-24" @default.
• W1966014546 creator A5009358349 @default.
• W1966014546 creator A5085621922 @default.
• W1966014546 creator A5086898973 @default.
• W1966014546 date "2006-08-01" @default.
• W1966014546 modified "2023-10-18" @default.
• W1966014546 title " -Hydroxybutyrate (GHB), -Butyrolactone (GBL), and 1,4-Butanediol (1,4-BD) Reduce the Volume of Cerebral Infarction in Rodent Transient Middle Cerebral Artery Occlusion" @default.
• W1966014546 cites W1966406869 @default.
• W1966014546 cites W1972520989 @default.
• W1966014546 cites W1985311213 @default.
• W1966014546 cites W1987164140 @default.
• W1966014546 cites W1990999165 @default.
• W1966014546 cites W1994719483 @default.
• W1966014546 cites W2008579214 @default.
• W1966014546 cites W2012175087 @default.
• W1966014546 cites W2013093936 @default.
• W1966014546 cites W2015074898 @default.
• W1966014546 cites W2021599573 @default.
• W1966014546 cites W2025741619 @default.
• W1966014546 cites W2035741102 @default.
• W1966014546 cites W2046248093 @default.
• W1966014546 cites W2046914383 @default.
• W1966014546 cites W2060116684 @default.
• W1966014546 cites W2060423418 @default.
• W1966014546 cites W2063680446 @default.
• W1966014546 cites W2102754758 @default.
• W1966014546 cites W2104298848 @default.
• W1966014546 cites W2104967914 @default.
• W1966014546 cites W2108133847 @default.
• W1966014546 cites W2139984643 @default.
• W1966014546 cites W2164937642 @default.
• W1966014546 cites W2169338081 @default.
• W1966014546 cites W2792583460 @default.
• W1966014546 cites W1981067791 @default.
• W1966014546 doi "https://doi.org/10.1196/annals.1369.054" @default.
• W1966014546 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17105951" @default.
• W1966014546 hasPublicationYear "2006" @default.
• W1966014546 type Work @default.
• W1966014546 sameAs 1966014546 @default.
• W1966014546 citedByCount "16" @default.
• W1966014546 countsByYear W19660145462012 @default.
• W1966014546 countsByYear W19660145462013 @default.
• W1966014546 countsByYear W19660145462015 @default.
• W1966014546 countsByYear W19660145462017 @default.
• W1966014546 countsByYear W19660145462020 @default.
• W1966014546 countsByYear W19660145462021 @default.
• W1966014546 countsByYear W19660145462022 @default.
• W1966014546 countsByYear W19660145462023 @default.
• W1966014546 crossrefType "journal-article" @default.
• W1966014546 hasAuthorship W1966014546A5009358349 @default.
• W1966014546 hasAuthorship W1966014546A5085621922 @default.
• W1966014546 hasAuthorship W1966014546A5086898973 @default.
• W1966014546 hasConcept C126322002 @default.
• W1966014546 hasConcept C161790260 @default.
• W1966014546 hasConcept C185592680 @default.
• W1966014546 hasConcept C25498285 @default.
• W1966014546 hasConcept C2775841333 @default.
• W1966014546 hasConcept C2777798775 @default.
• W1966014546 hasConcept C2778108642 @default.
• W1966014546 hasConcept C2779450755 @default.
• W1966014546 hasConcept C42219234 @default.
• W1966014546 hasConcept C500558357 @default.
• W1966014546 hasConcept C541997718 @default.
• W1966014546 hasConcept C55493867 @default.
• W1966014546 hasConcept C71924100 @default.
• W1966014546 hasConcept C98274493 @default.
• W1966014546 hasConceptScore W1966014546C126322002 @default.
• W1966014546 hasConceptScore W1966014546C161790260 @default.
• W1966014546 hasConceptScore W1966014546C185592680 @default.
• W1966014546 hasConceptScore W1966014546C25498285 @default.
• W1966014546 hasConceptScore W1966014546C2775841333 @default.
• W1966014546 hasConceptScore W1966014546C2777798775 @default.
• W1966014546 hasConceptScore W1966014546C2778108642 @default.
• W1966014546 hasConceptScore W1966014546C2779450755 @default.
• W1966014546 hasConceptScore W1966014546C42219234 @default.
• W1966014546 hasConceptScore W1966014546C500558357 @default.
• W1966014546 hasConceptScore W1966014546C541997718 @default.
• W1966014546 hasConceptScore W1966014546C55493867 @default.
• W1966014546 hasConceptScore W1966014546C71924100 @default.
• W1966014546 hasConceptScore W1966014546C98274493 @default.
• W1966014546 hasIssue "1" @default.
• W1966014546 hasLocation W19660145461 @default.
• W1966014546 hasLocation W19660145462 @default.
• W1966014546 hasOpenAccess W1966014546 @default.
• W1966014546 hasPrimaryLocation W19660145461 @default.
• W1966014546 hasRelatedWork W1972524512 @default.
• W1966014546 hasRelatedWork W1972549605 @default.
• W1966014546 hasRelatedWork W2042993171 @default.
• W1966014546 hasRelatedWork W2073402264 @default.
• W1966014546 hasRelatedWork W2167521548 @default.
• W1966014546 hasRelatedWork W2350050207 @default.
• W1966014546 hasRelatedWork W2368427005 @default.
• W1966014546 hasRelatedWork W2373759658 @default.
• W1966014546 hasRelatedWork W2414116801 @default.
• W1966014546 hasRelatedWork W2900463872 @default.
• W1966014546 hasVolume "1074" @default.
• W1966014546 isParatext "false" @default.

• next