FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966019053> ?p ?o ?g. }

• W1966019053 endingPage "957" @default.
• W1966019053 startingPage "951" @default.
• W1966019053 abstract "We have studied the effect of a topically administered glucocorticoid, fluticasone propionate (FP), on infiltration and activation of eosinophils in the nasal mucosa after provocation with allergen. Forty-four patients with seasonal allergic rhinitis entered a double-blind, crossover study in which they underwent treatment with either FP (200 micrograms once daily) or identical placebo for 2 weeks. Patients then underwent nasal-allergen provocation followed by nasal lavage and biopsy at one of several time points between 0 and 8 hours. Patients subsequently received the alternate treatment for 2 weeks before repeat allergen provocation, nasal lavage, and biopsy, as before. Biopsy specimens of nasal mucosa obtained during the immediate allergic response demonstrated an influx of eosinophils (stained by monoclonal antibody EG1) of similar magnitude during both FP and placebo treatment. Significantly, fewer eosinophils in these biopsy specimens were activated (stained by monoclonal antibody EG2) after treatment with FP compared with that after placebo treatment (median values, 8.8 and 36.6 cells per square millimeter, respectively; p less than 0.02). The concentration of eosinophil cationic protein in nasal lavage fluid was significantly elevated above baseline from 2 to 8 hours after allergen, and this increase was abolished by treatment with FP. These results suggest that topical glucocorticoids inhibit allergen-induced activation of eosinophils in allergic rhinitis." @default.
• W1966019053 created "2016-06-24" @default.
• W1966019053 creator A5006142596 @default.
• W1966019053 creator A5038908165 @default.
• W1966019053 creator A5042678499 @default.
• W1966019053 creator A5045817247 @default.
• W1966019053 creator A5046108434 @default.
• W1966019053 creator A5049064919 @default.
• W1966019053 creator A5067551607 @default.
• W1966019053 creator A5087201659 @default.
• W1966019053 date "1992-05-01" @default.
• W1966019053 modified "2023-09-23" @default.
• W1966019053 title "Topical glucocorticoids inhibit activation by allergen in the upper respiratory tract" @default.
• W1966019053 cites W113654845 @default.
• W1966019053 cites W1215160743 @default.
• W1966019053 cites W1982633250 @default.
• W1966019053 cites W1993645398 @default.
• W1966019053 cites W2012814430 @default.
• W1966019053 cites W2018493080 @default.
• W1966019053 cites W2029143226 @default.
• W1966019053 cites W2029933879 @default.
• W1966019053 cites W2030104278 @default.
• W1966019053 cites W2030376048 @default.
• W1966019053 cites W2030990965 @default.
• W1966019053 cites W2032830404 @default.
• W1966019053 cites W2037074544 @default.
• W1966019053 cites W2040514575 @default.
• W1966019053 cites W2043533730 @default.
• W1966019053 cites W2057937473 @default.
• W1966019053 cites W2060390160 @default.
• W1966019053 cites W2063322970 @default.
• W1966019053 cites W2079041573 @default.
• W1966019053 cites W2079061310 @default.
• W1966019053 cites W2080502516 @default.
• W1966019053 cites W2095381066 @default.
• W1966019053 cites W2106491377 @default.
• W1966019053 cites W2138878193 @default.
• W1966019053 cites W2161752363 @default.
• W1966019053 cites W2337026407 @default.
• W1966019053 cites W2399381939 @default.
• W1966019053 cites W2437988373 @default.
• W1966019053 doi "https://doi.org/10.1016/0091-6749(92)90217-p" @default.
• W1966019053 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1583252" @default.
• W1966019053 hasPublicationYear "1992" @default.
• W1966019053 type Work @default.
• W1966019053 sameAs 1966019053 @default.
• W1966019053 citedByCount "55" @default.
• W1966019053 countsByYear W19660190532012 @default.
• W1966019053 countsByYear W19660190532013 @default.
• W1966019053 countsByYear W19660190532019 @default.
• W1966019053 crossrefType "journal-article" @default.
• W1966019053 hasAuthorship W1966019053A5006142596 @default.
• W1966019053 hasAuthorship W1966019053A5038908165 @default.
• W1966019053 hasAuthorship W1966019053A5042678499 @default.
• W1966019053 hasAuthorship W1966019053A5045817247 @default.
• W1966019053 hasAuthorship W1966019053A5046108434 @default.
• W1966019053 hasAuthorship W1966019053A5049064919 @default.
• W1966019053 hasAuthorship W1966019053A5067551607 @default.
• W1966019053 hasAuthorship W1966019053A5087201659 @default.
• W1966019053 hasConcept C110586980 @default.
• W1966019053 hasConcept C126322002 @default.
• W1966019053 hasConcept C142724271 @default.
• W1966019053 hasConcept C203014093 @default.
• W1966019053 hasConcept C204787440 @default.
• W1966019053 hasConcept C207480886 @default.
• W1966019053 hasConcept C27081682 @default.
• W1966019053 hasConcept C2775934546 @default.
• W1966019053 hasConcept C2776042228 @default.
• W1966019053 hasConcept C2776472760 @default.
• W1966019053 hasConcept C2777037409 @default.
• W1966019053 hasConcept C2779028295 @default.
• W1966019053 hasConcept C2780510475 @default.
• W1966019053 hasConcept C2781212218 @default.
• W1966019053 hasConcept C2909814679 @default.
• W1966019053 hasConcept C59377437 @default.
• W1966019053 hasConcept C71924100 @default.
• W1966019053 hasConcept C88675164 @default.
• W1966019053 hasConcept C90924648 @default.
• W1966019053 hasConceptScore W1966019053C110586980 @default.
• W1966019053 hasConceptScore W1966019053C126322002 @default.
• W1966019053 hasConceptScore W1966019053C142724271 @default.
• W1966019053 hasConceptScore W1966019053C203014093 @default.
• W1966019053 hasConceptScore W1966019053C204787440 @default.
• W1966019053 hasConceptScore W1966019053C207480886 @default.
• W1966019053 hasConceptScore W1966019053C27081682 @default.
• W1966019053 hasConceptScore W1966019053C2775934546 @default.
• W1966019053 hasConceptScore W1966019053C2776042228 @default.
• W1966019053 hasConceptScore W1966019053C2776472760 @default.
• W1966019053 hasConceptScore W1966019053C2777037409 @default.
• W1966019053 hasConceptScore W1966019053C2779028295 @default.
• W1966019053 hasConceptScore W1966019053C2780510475 @default.
• W1966019053 hasConceptScore W1966019053C2781212218 @default.
• W1966019053 hasConceptScore W1966019053C2909814679 @default.
• W1966019053 hasConceptScore W1966019053C59377437 @default.
• W1966019053 hasConceptScore W1966019053C71924100 @default.
• W1966019053 hasConceptScore W1966019053C88675164 @default.
• W1966019053 hasConceptScore W1966019053C90924648 @default.
• W1966019053 hasIssue "5" @default.

• next