FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966069757> ?p ?o ?g. }

• W1966069757 endingPage "186" @default.
• W1966069757 startingPage "179" @default.
• W1966069757 abstract "Paramphistomiasis causes enteritis and anemia in livestocks and result in substantial production and economic losses. It is considered a neglected tropical disease, with no effective trematodicidal compound for treatment. Plumbagin (PB), a compound founds to be rich in the roots of Plumbago indica, is a naphthoquinone derivatives which can induce oxidative stress in parasites. In this study we have evaluated the anthelmintic activity of PB against adult Paramphistomum cervi by incubating the parasites in M-199 medium containing 0.1, 1.0, 10 and 100 μg/ml of the PB, and albendazole (ABZ) at the concentration of 100 μg/ml as the positive control, for 3, 6, 12 and 24 h, using relative motility (RM) assay and observed by scanning electron microscopy (SEM). After 12 h exposure with 100 μg/ml ABZ, flukes showed decreased contraction and motility. At 24 h incubation they showed only active movement of some part of the body. The PB-treated flukes at all concentrations showed rapid decrease of motility at 3 h incubation. In 0.1, 1.0 and 10 μg/ml of PB, the RM values were decreased sharply from 3 to 12 h, and then they were killed since 12 h in the incubation with 10 μg/ml of PB. The highest parasite mortality was found as early as 3h when they were incubated with 100 μg/ml of PB. The morphological changes on the tegumental surface were similar in both flukes treated with ABZ and PB, which sequentially comprised of swelling, followed by blebbings that later ruptured, leading to the erosion and desquamation of the tegument syncytium. As the result, lesions were formed which exposed the basal lamina. The damage appeared more severe on the ventral than the dorsal surface, and earlier on the anterior part and lateral margins of middle third when compared to the posterior part of the parasites's bodies. The severity and rapidity of the damages were enhanced with increasing concentration of PB, which showed stronger activity than ABZ. Hence, PB has a potential to be an anthelmintic drug against adult P.cervi." @default.
• W1966069757 created "2016-06-24" @default.
• W1966069757 creator A5032061768 @default.
• W1966069757 creator A5045144953 @default.
• W1966069757 creator A5054238100 @default.
• W1966069757 creator A5076919610 @default.
• W1966069757 creator A5081414334 @default.
• W1966069757 date "2013-02-01" @default.
• W1966069757 modified "2023-09-25" @default.
• W1966069757 title "Paramphistomum cervi: The in vitro effect of plumbagin on motility, survival and tegument structure" @default.
• W1966069757 cites W1599674963 @default.
• W1966069757 cites W1696227661 @default.
• W1966069757 cites W1985726772 @default.
• W1966069757 cites W1994743126 @default.
• W1966069757 cites W1994795924 @default.
• W1966069757 cites W1997870386 @default.
• W1966069757 cites W2006826613 @default.
• W1966069757 cites W2030181833 @default.
• W1966069757 cites W2052843521 @default.
• W1966069757 cites W2056335884 @default.
• W1966069757 cites W2058005680 @default.
• W1966069757 cites W2060647890 @default.
• W1966069757 cites W2064486727 @default.
• W1966069757 cites W2072610915 @default.
• W1966069757 cites W2074252192 @default.
• W1966069757 cites W2080796517 @default.
• W1966069757 cites W2088719505 @default.
• W1966069757 cites W2088788271 @default.
• W1966069757 cites W2092893785 @default.
• W1966069757 cites W2096233180 @default.
• W1966069757 cites W2114326250 @default.
• W1966069757 cites W2136016595 @default.
• W1966069757 cites W2155699161 @default.
• W1966069757 cites W2156814302 @default.
• W1966069757 cites W2168597394 @default.
• W1966069757 cites W2327979819 @default.
• W1966069757 doi "https://doi.org/10.1016/j.exppara.2012.11.018" @default.
• W1966069757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23206952" @default.
• W1966069757 hasPublicationYear "2013" @default.
• W1966069757 type Work @default.
• W1966069757 sameAs 1966069757 @default.
• W1966069757 citedByCount "19" @default.
• W1966069757 countsByYear W19660697572014 @default.
• W1966069757 countsByYear W19660697572015 @default.
• W1966069757 countsByYear W19660697572016 @default.
• W1966069757 countsByYear W19660697572017 @default.
• W1966069757 countsByYear W19660697572019 @default.
• W1966069757 countsByYear W19660697572020 @default.
• W1966069757 countsByYear W19660697572021 @default.
• W1966069757 countsByYear W19660697572022 @default.
• W1966069757 countsByYear W19660697572023 @default.
• W1966069757 crossrefType "journal-article" @default.
• W1966069757 hasAuthorship W1966069757A5032061768 @default.
• W1966069757 hasAuthorship W1966069757A5045144953 @default.
• W1966069757 hasAuthorship W1966069757A5054238100 @default.
• W1966069757 hasAuthorship W1966069757A5076919610 @default.
• W1966069757 hasAuthorship W1966069757A5081414334 @default.
• W1966069757 hasConcept C146998594 @default.
• W1966069757 hasConcept C153911025 @default.
• W1966069757 hasConcept C159047783 @default.
• W1966069757 hasConcept C16685009 @default.
• W1966069757 hasConcept C18903297 @default.
• W1966069757 hasConcept C202751555 @default.
• W1966069757 hasConcept C25642318 @default.
• W1966069757 hasConcept C2776908094 @default.
• W1966069757 hasConcept C2777065887 @default.
• W1966069757 hasConcept C2780532915 @default.
• W1966069757 hasConcept C54355233 @default.
• W1966069757 hasConcept C55493867 @default.
• W1966069757 hasConcept C58207958 @default.
• W1966069757 hasConcept C59822182 @default.
• W1966069757 hasConcept C71924100 @default.
• W1966069757 hasConcept C86803240 @default.
• W1966069757 hasConceptScore W1966069757C146998594 @default.
• W1966069757 hasConceptScore W1966069757C153911025 @default.
• W1966069757 hasConceptScore W1966069757C159047783 @default.
• W1966069757 hasConceptScore W1966069757C16685009 @default.
• W1966069757 hasConceptScore W1966069757C18903297 @default.
• W1966069757 hasConceptScore W1966069757C202751555 @default.
• W1966069757 hasConceptScore W1966069757C25642318 @default.
• W1966069757 hasConceptScore W1966069757C2776908094 @default.
• W1966069757 hasConceptScore W1966069757C2777065887 @default.
• W1966069757 hasConceptScore W1966069757C2780532915 @default.
• W1966069757 hasConceptScore W1966069757C54355233 @default.
• W1966069757 hasConceptScore W1966069757C55493867 @default.
• W1966069757 hasConceptScore W1966069757C58207958 @default.
• W1966069757 hasConceptScore W1966069757C59822182 @default.
• W1966069757 hasConceptScore W1966069757C71924100 @default.
• W1966069757 hasConceptScore W1966069757C86803240 @default.
• W1966069757 hasFunder F4320322574 @default.
• W1966069757 hasFunder F4320322614 @default.
• W1966069757 hasFunder F4320324072 @default.
• W1966069757 hasIssue "2" @default.
• W1966069757 hasLocation W19660697571 @default.
• W1966069757 hasLocation W19660697572 @default.
• W1966069757 hasOpenAccess W1966069757 @default.
• W1966069757 hasPrimaryLocation W19660697571 @default.
• W1966069757 hasRelatedWork W1966069757 @default.

• next