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- W1966077037 abstract "Reports on zonal aganglionosis of the bowel are very rare and the few cases reported concern colon and rectum. We present a case of segmental aganglionosis of the jejunum in a 2-months-old boy. He had to be operated upon twice because of an ileus of the short bowel. At the second operation, a 10 cm long narrow segment of the jejunum was resected. The histological examination revealed a segmental aganglionosis of the plexus myentericus. Possible causes of this rare zonal aganglionosis could be: 1. Local damage of the plexus myentericus through anoxia. 2. Primary abnormity in the gastrointestinal anlage. 3. An intrauterine inflammation. 4. A double migration and development gradient of the precursors of the neuroblasts, from each end to the middle of the gut. A defect in the microenvironment of the enteric neurons would result in their failure in differentiation. This possible explanation would challenge the accepted theory of pathogenesis of colonic aganglionosis." @default.
- W1966077037 created "2016-06-24" @default.
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- W1966077037 date "1988-12-01" @default.
- W1966077037 modified "2023-09-27" @default.
- W1966077037 title "Segmentale Aganglionose des Dünndarms - Mythos oder Wirklichkeit? (Eine Falldarstellung)" @default.
- W1966077037 doi "https://doi.org/10.1055/s-2008-1043501" @default.
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