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• W1966079593 abstract "ObjectivesTo evaluate the presence of human T-lymphotropic virus type 1 (HTLV-1) infection in isolated rural communities in the southern Andes of Peru.MethodsWe conducted a cross-sectional study in five communities located in three provinces in Ayacucho, Peru. The five communities are located at >3000 meters above sea level and are mainly rural, and more than 85% of the population speaks Quechua. Volunteers aged 12 years and older were included. Clinical and epidemiological data were collected, along with a blood sample for serological testing.ResultsWe included 397 participants; their median age was 41 years (interquartile range 31–57 years) and 69% were women. According to our definitions, 98% were of Quechua origin. HTLV-1 was diagnosed in 11 people: 0/164 in Cangallo, 3/154 (2%) in Vilcashuaman, and 8/79 (10%) in Parinacochas. There were no cases of HTLV-2. All the HTLV-1-positive participants were born in Ayacucho and were of Quechua origin; they ranged in age from 29 to 87 years (median 56 years) and 10/11 were women. Ten were apparently healthy, and one woman was diagnosed with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Three out of 11 had a family member with a lower limb impairment compatible with HAM/TSP.ConclusionThe fact that HTLV-1 infection was present in two out of three provinces suggests that HTLV-1 could be highly endemic in the southern Andes in the Quechua population." @default.
• W1966079593 created "2016-06-24" @default.
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• W1966079593 date "2014-02-01" @default.
• W1966079593 modified "2023-09-30" @default.
• W1966079593 title "Human T-lymphotropic virus type 1 infection is frequent in rural communities of the southern Andes of Peru" @default.
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• W1966079593 doi "https://doi.org/10.1016/j.ijid.2013.10.005" @default.
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