FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966112021> ?p ?o ?g. }

• W1966112021 abstract "Problems associated with stimulant use have been linked to frontocingulate, insular, and thalamic dysfunction during decision-making and alterations in interoceptive processing. However, little is known about how interoception and decision-making interact and contribute to dysfunctions that promote the transition from recreational drug use to abuse or dependence. Here, we investigate brain activation in response to reward, punishment, and uncertainty during an aversive interoceptive challenge in current and former stimulant (cocaine and amphetamine) users using functional magnetic resonance imaging (fMRI). Young adults previously identified as recreational users (n=184) were followed up three years later. Of these, 18 individuals progressed to problem stimulant use (PSU), whereas 15 desisted stimulant use (DSU). PSU, DSU, and 14 healthy comparison subjects (CTL) performed a two-choice prediction task at three fixed error rates (20%=reward, 50%=uncertainty, 80%=punishment) during which they anticipated and experienced episodes of inspiratory breathing load. Although groups did not differ in insula activation or subjective breathing load ratings, PSU exhibited lower right inferior frontal gyrus (IFG) and bilateral anterior cingulate (ACC) activation than DSU and CTL during aversive interoceptive processing as well as lower right IFG in response to decision making involving uncertainty. However, PSU exhibited greater bilateral IFG activation than DSU and CTL while making choices within the context of punishing feedback, and both PSU and DSU showed lower thalamic activation during breathing load than CTL. Findings suggest that frontocingulate attenuation, reflecting reduced resources devoted to goal maintenance and action selection in the presence of uncertainty and interoceptive perturbations, may be a biomarker for susceptibility to problem stimulant use." @default.
• W1966112021 created "2016-06-24" @default.
• W1966112021 creator A5030047212 @default.
• W1966112021 creator A5054660259 @default.
• W1966112021 creator A5063018096 @default.
• W1966112021 creator A5081736253 @default.
• W1966112021 creator A5087626094 @default.
• W1966112021 date "2013-01-01" @default.
• W1966112021 modified "2023-10-07" @default.
• W1966112021 title "Altered frontocingulate activation during aversive interoceptive processing in young adults transitioning to problem stimulant use" @default.
• W1966112021 cites W1569173481 @default.
• W1966112021 cites W1590230971 @default.
• W1966112021 cites W1594303435 @default.
• W1966112021 cites W1804828504 @default.
• W1966112021 cites W1853321344 @default.
• W1966112021 cites W1973104542 @default.
• W1966112021 cites W1973541229 @default.
• W1966112021 cites W1975799116 @default.
• W1966112021 cites W1976397511 @default.
• W1966112021 cites W1988343218 @default.
• W1966112021 cites W1988557303 @default.
• W1966112021 cites W1995751463 @default.
• W1966112021 cites W1995932939 @default.
• W1966112021 cites W1999673284 @default.
• W1966112021 cites W2007153366 @default.
• W1966112021 cites W2019401805 @default.
• W1966112021 cites W2022500640 @default.
• W1966112021 cites W2022529676 @default.
• W1966112021 cites W2027543384 @default.
• W1966112021 cites W2043621158 @default.
• W1966112021 cites W2046709366 @default.
• W1966112021 cites W2050448562 @default.
• W1966112021 cites W2054515032 @default.
• W1966112021 cites W2054590164 @default.
• W1966112021 cites W2054966521 @default.
• W1966112021 cites W2064529195 @default.
• W1966112021 cites W2065591330 @default.
• W1966112021 cites W2066046229 @default.
• W1966112021 cites W2070810386 @default.
• W1966112021 cites W2071330909 @default.
• W1966112021 cites W2083375686 @default.
• W1966112021 cites W2084585578 @default.
• W1966112021 cites W2085143064 @default.
• W1966112021 cites W2089160153 @default.
• W1966112021 cites W2089163599 @default.
• W1966112021 cites W2093072466 @default.
• W1966112021 cites W2105558714 @default.
• W1966112021 cites W2106937090 @default.
• W1966112021 cites W2107790366 @default.
• W1966112021 cites W2108599940 @default.
• W1966112021 cites W2111609296 @default.
• W1966112021 cites W2114006934 @default.
• W1966112021 cites W2116283675 @default.
• W1966112021 cites W2117140276 @default.
• W1966112021 cites W2120604774 @default.
• W1966112021 cites W2123029555 @default.
• W1966112021 cites W2125778686 @default.
• W1966112021 cites W2128981193 @default.
• W1966112021 cites W2129990946 @default.
• W1966112021 cites W2130434337 @default.
• W1966112021 cites W2130887123 @default.
• W1966112021 cites W2131379141 @default.
• W1966112021 cites W2131510747 @default.
• W1966112021 cites W2131884052 @default.
• W1966112021 cites W2135163016 @default.
• W1966112021 cites W2136022845 @default.
• W1966112021 cites W2139155586 @default.
• W1966112021 cites W2141532181 @default.
• W1966112021 cites W2142213531 @default.
• W1966112021 cites W2142823391 @default.
• W1966112021 cites W2154543189 @default.
• W1966112021 cites W2165715451 @default.
• W1966112021 cites W2167010758 @default.
• W1966112021 cites W2167420848 @default.
• W1966112021 cites W2237085184 @default.
• W1966112021 cites W2582743722 @default.
• W1966112021 cites W3086315876 @default.
• W1966112021 doi "https://doi.org/10.3389/fnsys.2013.00089" @default.
• W1966112021 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3828508" @default.
• W1966112021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24298242" @default.
• W1966112021 hasPublicationYear "2013" @default.
• W1966112021 type Work @default.
• W1966112021 sameAs 1966112021 @default.
• W1966112021 citedByCount "19" @default.
• W1966112021 countsByYear W19661120212014 @default.
• W1966112021 countsByYear W19661120212015 @default.
• W1966112021 countsByYear W19661120212016 @default.
• W1966112021 countsByYear W19661120212018 @default.
• W1966112021 countsByYear W19661120212019 @default.
• W1966112021 countsByYear W19661120212020 @default.
• W1966112021 countsByYear W19661120212022 @default.
• W1966112021 countsByYear W19661120212023 @default.
• W1966112021 crossrefType "journal-article" @default.
• W1966112021 hasAuthorship W1966112021A5030047212 @default.
• W1966112021 hasAuthorship W1966112021A5054660259 @default.
• W1966112021 hasAuthorship W1966112021A5063018096 @default.
• W1966112021 hasAuthorship W1966112021A5081736253 @default.
• W1966112021 hasAuthorship W1966112021A5087626094 @default.
• W1966112021 hasBestOaLocation W19661120211 @default.
• W1966112021 hasConcept C104996578 @default.

• next