FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966116164> ?p ?o ?g. }

• W1966116164 endingPage "196" @default.
• W1966116164 startingPage "191" @default.
• W1966116164 abstract "Elevated production of cysteinyl leukotrienes (cysLTs) from sinus tissues and abundant sinus eosinophils are characteristic features of chronic hyperplastic eosinophilic sinusitis (CHS). CysLTs exert their action through G-protein-coupled receptors named cysLTs receptor type I (cysLT1R) and type II (cysLT2R). These expressions of cysLT receptors in the sinus mucosa have yet to be clarified and the relationship between eosinophilia and the expression of these receptors remains obscure. We compared the expressions of cysLT1R and cysLT2R in the sinus mucosa in patients with CHS, non-eosinophilic chronic sinusitis (NECS), and control sinus tissues; and analyzed the correlation between the expression of CysLTRs and the presence of sinus eosinophils by immunohistochemistry and real-time PCR. A significantly higher percentage of eosinophils expressing cysLT2R protein was observed in patients with CHS compared with NECS and controls. In addition, cysLT2R mRNA expression in CHS was significantly higher than in NECS and controls. Furthermore, a positive correlation was observed between cysLT2R mRNA expression and the number of infiltrated eosinophils. In contrast, the cysLT1R mRNA expression did not differ significantly among these groups. The effect of cysLTs on sinus eosinophils may be mediated through the cysLT2R in patients with CHS. These results may suggest the therapeutic benefit of cysLT2R antagonists in CHS." @default.
• W1966116164 created "2016-06-24" @default.
• W1966116164 creator A5007763021 @default.
• W1966116164 creator A5019406796 @default.
• W1966116164 creator A5035730269 @default.
• W1966116164 creator A5038337339 @default.
• W1966116164 creator A5038504434 @default.
• W1966116164 creator A5061538474 @default.
• W1966116164 creator A5087150619 @default.
• W1966116164 date "2009-01-01" @default.
• W1966116164 modified "2023-09-27" @default.
• W1966116164 title "Expression of cysLT1 and cysLT2 Receptor in Chronic Hyperplastic Eosinophilic Sinusitis" @default.
• W1966116164 cites W1936798053 @default.
• W1966116164 cites W1974965886 @default.
• W1966116164 cites W1983262394 @default.
• W1966116164 cites W2004034703 @default.
• W1966116164 cites W2016805863 @default.
• W1966116164 cites W2023319724 @default.
• W1966116164 cites W2028170289 @default.
• W1966116164 cites W2033514267 @default.
• W1966116164 cites W2034133667 @default.
• W1966116164 cites W2096768293 @default.
• W1966116164 cites W2107277218 @default.
• W1966116164 cites W2116594128 @default.
• W1966116164 cites W2144831051 @default.
• W1966116164 cites W2146319740 @default.
• W1966116164 cites W2171451814 @default.
• W1966116164 doi "https://doi.org/10.1267/ahc.09031" @default.
• W1966116164 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2808502" @default.
• W1966116164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20126572" @default.
• W1966116164 hasPublicationYear "2009" @default.
• W1966116164 type Work @default.
• W1966116164 sameAs 1966116164 @default.
• W1966116164 citedByCount "3" @default.
• W1966116164 countsByYear W19661161642013 @default.
• W1966116164 countsByYear W19661161642015 @default.
• W1966116164 crossrefType "journal-article" @default.
• W1966116164 hasAuthorship W1966116164A5007763021 @default.
• W1966116164 hasAuthorship W1966116164A5019406796 @default.
• W1966116164 hasAuthorship W1966116164A5035730269 @default.
• W1966116164 hasAuthorship W1966116164A5038337339 @default.
• W1966116164 hasAuthorship W1966116164A5038504434 @default.
• W1966116164 hasAuthorship W1966116164A5061538474 @default.
• W1966116164 hasAuthorship W1966116164A5087150619 @default.
• W1966116164 hasBestOaLocation W19661161641 @default.
• W1966116164 hasConcept C10162356 @default.
• W1966116164 hasConcept C126322002 @default.
• W1966116164 hasConcept C142724271 @default.
• W1966116164 hasConcept C157369684 @default.
• W1966116164 hasConcept C170493617 @default.
• W1966116164 hasConcept C203014093 @default.
• W1966116164 hasConcept C204232928 @default.
• W1966116164 hasConcept C2776407911 @default.
• W1966116164 hasConcept C2777129736 @default.
• W1966116164 hasConcept C2777768476 @default.
• W1966116164 hasConcept C2779758542 @default.
• W1966116164 hasConcept C2781390199 @default.
• W1966116164 hasConcept C2994554258 @default.
• W1966116164 hasConcept C59822182 @default.
• W1966116164 hasConcept C71924100 @default.
• W1966116164 hasConcept C86803240 @default.
• W1966116164 hasConceptScore W1966116164C10162356 @default.
• W1966116164 hasConceptScore W1966116164C126322002 @default.
• W1966116164 hasConceptScore W1966116164C142724271 @default.
• W1966116164 hasConceptScore W1966116164C157369684 @default.
• W1966116164 hasConceptScore W1966116164C170493617 @default.
• W1966116164 hasConceptScore W1966116164C203014093 @default.
• W1966116164 hasConceptScore W1966116164C204232928 @default.
• W1966116164 hasConceptScore W1966116164C2776407911 @default.
• W1966116164 hasConceptScore W1966116164C2777129736 @default.
• W1966116164 hasConceptScore W1966116164C2777768476 @default.
• W1966116164 hasConceptScore W1966116164C2779758542 @default.
• W1966116164 hasConceptScore W1966116164C2781390199 @default.
• W1966116164 hasConceptScore W1966116164C2994554258 @default.
• W1966116164 hasConceptScore W1966116164C59822182 @default.
• W1966116164 hasConceptScore W1966116164C71924100 @default.
• W1966116164 hasConceptScore W1966116164C86803240 @default.
• W1966116164 hasIssue "6" @default.
• W1966116164 hasLocation W19661161641 @default.
• W1966116164 hasLocation W19661161642 @default.
• W1966116164 hasLocation W19661161643 @default.
• W1966116164 hasLocation W19661161644 @default.
• W1966116164 hasOpenAccess W1966116164 @default.
• W1966116164 hasPrimaryLocation W19661161641 @default.
• W1966116164 hasRelatedWork W1966116164 @default.
• W1966116164 hasRelatedWork W1976514934 @default.
• W1966116164 hasRelatedWork W2016805863 @default.
• W1966116164 hasRelatedWork W2044671856 @default.
• W1966116164 hasRelatedWork W2083097301 @default.
• W1966116164 hasRelatedWork W2314615215 @default.
• W1966116164 hasRelatedWork W2367741495 @default.
• W1966116164 hasRelatedWork W2376699134 @default.
• W1966116164 hasRelatedWork W2386062943 @default.
• W1966116164 hasRelatedWork W2397656092 @default.
• W1966116164 hasVolume "42" @default.
• W1966116164 isParatext "false" @default.
• W1966116164 isRetracted "false" @default.
• W1966116164 magId "1966116164" @default.

• next