FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966128212> ?p ?o ?g. }

• W1966128212 endingPage "2117" @default.
• W1966128212 startingPage "2106" @default.
• W1966128212 abstract "Strict maternal inheritance is considered a hallmark of animal mtDNA. Although recent reports suggest that paternal leakage occurs in a broad range of species, it is still considered an exceptionally rare event. To evaluate the impact of paternal leakage on the evolution of mtDNA, it is essential to reliably estimate the frequency of paternal leakage in natural populations. Using allele-specific real-time quantitative PCR (RT-qPCR), we show that heteroplasmy is common in natural populations with at least 14% of the individuals carrying multiple mitochondrial haplotypes. However, the average frequency of the minor mtDNA haplotype is low (0.8%), which suggests that this pervasive heteroplasmy has not been noticed before due to a lack of power in sequencing surveys. Based on the distribution of mtDNA haplotypes in the offspring of heteroplasmic mothers, we found no evidence for strong selection against one of the haplotypes. We estimated that the rate of paternal leakage is 6% and that at least 100 generations are required for complete sorting of mtDNA haplotypes. Despite the high proportion of heteroplasmic individuals in natural populations, we found no evidence for recombination between mtDNA molecules, suggesting that either recombination is rare or recombinant haplotypes are counter-selected. Our results indicate that evolutionary studies using mtDNA as a marker might be biased by paternal leakage in this species." @default.
• W1966128212 created "2016-06-24" @default.
• W1966128212 creator A5019579446 @default.
• W1966128212 creator A5054925123 @default.
• W1966128212 creator A5059827997 @default.
• W1966128212 date "2013-03-04" @default.
• W1966128212 modified "2023-10-11" @default.
• W1966128212 title "Extensive paternal mt<scp>DNA</scp>leakage in natural populations of<i><scp>D</scp>rosophila melanogaster</i>" @default.
• W1966128212 cites W1561497451 @default.
• W1966128212 cites W1914058246 @default.
• W1966128212 cites W1916532806 @default.
• W1966128212 cites W1963715201 @default.
• W1966128212 cites W1966461639 @default.
• W1966128212 cites W1980680088 @default.
• W1966128212 cites W1981161568 @default.
• W1966128212 cites W1983973181 @default.
• W1966128212 cites W1990258169 @default.
• W1966128212 cites W1992224295 @default.
• W1966128212 cites W1997360166 @default.
• W1966128212 cites W2000454435 @default.
• W1966128212 cites W2003595434 @default.
• W1966128212 cites W2003672519 @default.
• W1966128212 cites W2006662323 @default.
• W1966128212 cites W2006876928 @default.
• W1966128212 cites W2014972109 @default.
• W1966128212 cites W2015897815 @default.
• W1966128212 cites W2019219052 @default.
• W1966128212 cites W2033563126 @default.
• W1966128212 cites W2044221417 @default.
• W1966128212 cites W2049622181 @default.
• W1966128212 cites W2055026289 @default.
• W1966128212 cites W2055298722 @default.
• W1966128212 cites W2064063117 @default.
• W1966128212 cites W2065796860 @default.
• W1966128212 cites W2066414591 @default.
• W1966128212 cites W2068050243 @default.
• W1966128212 cites W2075177094 @default.
• W1966128212 cites W2079161571 @default.
• W1966128212 cites W2081949803 @default.
• W1966128212 cites W2086399579 @default.
• W1966128212 cites W2090211976 @default.
• W1966128212 cites W2093810411 @default.
• W1966128212 cites W2094747725 @default.
• W1966128212 cites W2098561776 @default.
• W1966128212 cites W2101243779 @default.
• W1966128212 cites W2101827100 @default.
• W1966128212 cites W2114456703 @default.
• W1966128212 cites W2115854588 @default.
• W1966128212 cites W2116398302 @default.
• W1966128212 cites W2116652744 @default.
• W1966128212 cites W2118094114 @default.
• W1966128212 cites W2124633191 @default.
• W1966128212 cites W2129452041 @default.
• W1966128212 cites W2129672566 @default.
• W1966128212 cites W2133992850 @default.
• W1966128212 cites W2138738916 @default.
• W1966128212 cites W2140481050 @default.
• W1966128212 cites W2141602140 @default.
• W1966128212 cites W2142249333 @default.
• W1966128212 cites W2143900692 @default.
• W1966128212 cites W2144708548 @default.
• W1966128212 cites W2154845780 @default.
• W1966128212 cites W2155645165 @default.
• W1966128212 cites W2156592409 @default.
• W1966128212 cites W2158714788 @default.
• W1966128212 cites W2162906788 @default.
• W1966128212 cites W2164418313 @default.
• W1966128212 cites W2166817837 @default.
• W1966128212 cites W2186021997 @default.
• W1966128212 cites W2346949914 @default.
• W1966128212 cites W2770504902 @default.
• W1966128212 doi "https://doi.org/10.1111/mec.12256" @default.
• W1966128212 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3659417" @default.
• W1966128212 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23452233" @default.
• W1966128212 hasPublicationYear "2013" @default.
• W1966128212 type Work @default.
• W1966128212 sameAs 1966128212 @default.
• W1966128212 citedByCount "55" @default.
• W1966128212 countsByYear W19661282122013 @default.
• W1966128212 countsByYear W19661282122014 @default.
• W1966128212 countsByYear W19661282122015 @default.
• W1966128212 countsByYear W19661282122016 @default.
• W1966128212 countsByYear W19661282122017 @default.
• W1966128212 countsByYear W19661282122018 @default.
• W1966128212 countsByYear W19661282122019 @default.
• W1966128212 countsByYear W19661282122020 @default.
• W1966128212 countsByYear W19661282122021 @default.
• W1966128212 countsByYear W19661282122022 @default.
• W1966128212 countsByYear W19661282122023 @default.
• W1966128212 crossrefType "journal-article" @default.
• W1966128212 hasAuthorship W1966128212A5019579446 @default.
• W1966128212 hasAuthorship W1966128212A5054925123 @default.
• W1966128212 hasAuthorship W1966128212A5059827997 @default.
• W1966128212 hasBestOaLocation W19661282121 @default.
• W1966128212 hasConcept C104317684 @default.
• W1966128212 hasConcept C144024400 @default.
• W1966128212 hasConcept C149923435 @default.
• W1966128212 hasConcept C156695909 @default.

• next