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• W1966128411 abstract "Chemical screening of the ethyl acetate extract from the marine-derived Streptomyces sp. isolate Mei37 resulted in five isoquinolinequinones, four new derivatives, mansouramycin A-D (1, 3-5), and the known 3-methyl-7-(methylamino)-5,8-isoquinolinedione (2). Their structures were elucidated by NMR and MS techniques and by comparison with related compounds. Cytotoxicity profiling of the mansouramycins in a panel of up to 36 tumor cell lines indicated significant cytotoxicity of several derivatives, with pronounced selectivity for non-small cell lung cancer, breast cancer, melanoma, and prostate cancer cells." @default.
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• W1966128411 date "2009-11-18" @default.
• W1966128411 modified "2023-10-14" @default.
• W1966128411 title "Mansouramycins A−D, Cytotoxic Isoquinolinequinones from a Marine Streptomycete" @default.
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• W1966128411 doi "https://doi.org/10.1021/np900160g" @default.
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