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- W1966141166 abstract "Abstract Forty-six subjects who gave positive cutaneous reactions to benzylpenicilloyl-human serum albumin (BPO-HSA) or benzylpenicillin (Pc G) were further skin-tested with 14 kinds of test materials: benzylpenicillin, benzylpenicilloyl-epsilon-aminocaproate (BPO-EACA), divalent BPO-hexamethylenediamine, polyvalent BPO-human serum albumin conjugates, polyvalent BPO-poly-L-lysine conjugates, polyvalent penicilloyl-HSA conjugates of synthetic penicillins, polyvalent 6-aminopenicillanic acid-HSA conjugate, polyvalent cephalothin-HSA conjugate, and polyvalent conjugates of the acyl side-chain compounds of penicillins. Correlation coefficients among the diameters of wheals elicited with these test materials varied with each test antigen. In order to evaluate the heterogeneity of combining sites of the human skin-sensitizing antibodies, factor analysis was carried out. Eight independent factors were elucidated, which suggests that there are at least 8 different kinds of antibody molecules with respect to their binding properties for the different penicillin compounds." @default.
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- W1966141166 date "1968-08-01" @default.
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- W1966141166 title "The heterogeneity of human antipenicillin skin-sensitizing antibodies" @default.
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- W1966141166 doi "https://doi.org/10.1016/0021-8707(68)90136-6" @default.
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