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• W1966170250 abstract "Convergent evolution provides a rare, natural experiment with which to test the predictability of adaptation at the molecular level. Little is known about the molecular basis of convergence over macro-evolutionary timescales. Here we use a combination of positional cloning, population genomic resequencing, association mapping and developmental data to demonstrate that positionally orthologous nucleotide variants in the upstream region of the same gene, WntA, are responsible for parallel mimetic variation in two butterfly lineages that diverged >65 million years ago. Furthermore, characterization of spatial patterns of WntA expression during development suggests that alternative regulatory mechanisms underlie wing pattern variation in each system. Taken together, our results reveal a strikingly predictable molecular basis for phenotypic convergence over deep evolutionary time." @default.
• W1966170250 created "2016-06-24" @default.
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• W1966170250 date "2014-09-08" @default.
• W1966170250 modified "2023-10-07" @default.
• W1966170250 title "Ancient homology underlies adaptive mimetic diversity across butterflies" @default.
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• W1966170250 doi "https://doi.org/10.1038/ncomms5817" @default.
• W1966170250 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4183220" @default.
• W1966170250 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25198507" @default.
• W1966170250 hasPublicationYear "2014" @default.
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