FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966193807> ?p ?o ?g. }

• W1966193807 endingPage "103" @default.
• W1966193807 startingPage "92" @default.
• W1966193807 abstract "Recognition of the importance of lipid signaling in cellular function has led to rapid progress in the technology of lipid analysis. Measurements of lipid species changes are central to defining the networks of cell signaling (e.g., receptor activation by hormones or drugs) and lipids are involved in many biochemical and pathological processes. During the last several years our laboratory has focused on developing efficient methods for extraction of glycerophospholipids from biological systems and their detection and identification by mass spectrometry. We analyze phospholipid changes in mammalian cells as a result of a defined ligand stimulation strategy that supports the research questions of the consortium. The improvement of mass spectrometry techniques for phospholipid analysis combined with sophisticated computational methods developed in our group has facilitated simultaneous analysis of hundreds of phospholipid species in mammalian cells. This information is presented as Lipid Arrays (or more precisely as virtual arrays) and allows identification of temporal changes in membrane phospholipid species between two contrasting biological conditions (e.g., unstimulated basal vs. stimulated or as a contrast between normal and disease stages). Using the lipidomics approach, we are able to identify approximately 450 phospholipid species from total membrane extracts and qualitatively measure pattern response changes initiated by cell surface receptors. As such, this approach facilitates the elucidation of the metabolic changes induced by a perturbation in the cell and recognition of patterns of signaling." @default.
• W1966193807 created "2016-06-24" @default.
• W1966193807 creator A5002994981 @default.
• W1966193807 creator A5005600452 @default.
• W1966193807 creator A5029530124 @default.
• W1966193807 creator A5061495260 @default.
• W1966193807 date "2006-06-01" @default.
• W1966193807 modified "2023-10-10" @default.
• W1966193807 title "Lipidomics: An analysis of cellular lipids by ESI-MS" @default.
• W1966193807 cites W1534835840 @default.
• W1966193807 cites W1829464403 @default.
• W1966193807 cites W1890757015 @default.
• W1966193807 cites W1967722034 @default.
• W1966193807 cites W1973671612 @default.
• W1966193807 cites W1974551552 @default.
• W1966193807 cites W1980943890 @default.
• W1966193807 cites W1986448105 @default.
• W1966193807 cites W1998413819 @default.
• W1966193807 cites W2000589601 @default.
• W1966193807 cites W2004574784 @default.
• W1966193807 cites W2006209403 @default.
• W1966193807 cites W2018265125 @default.
• W1966193807 cites W2026541693 @default.
• W1966193807 cites W2027030291 @default.
• W1966193807 cites W2036618934 @default.
• W1966193807 cites W2037881903 @default.
• W1966193807 cites W2042009328 @default.
• W1966193807 cites W2045440171 @default.
• W1966193807 cites W2066093283 @default.
• W1966193807 cites W2073292063 @default.
• W1966193807 cites W2074619822 @default.
• W1966193807 cites W2077727777 @default.
• W1966193807 cites W2080078957 @default.
• W1966193807 cites W2081380820 @default.
• W1966193807 cites W2087839268 @default.
• W1966193807 cites W2094561952 @default.
• W1966193807 cites W2096775596 @default.
• W1966193807 cites W2120191364 @default.
• W1966193807 cites W2140561555 @default.
• W1966193807 cites W2152311269 @default.
• W1966193807 cites W2158138282 @default.
• W1966193807 cites W2228000309 @default.
• W1966193807 cites W2951052348 @default.
• W1966193807 doi "https://doi.org/10.1016/j.ymeth.2006.05.014" @default.
• W1966193807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16846739" @default.
• W1966193807 hasPublicationYear "2006" @default.
• W1966193807 type Work @default.
• W1966193807 sameAs 1966193807 @default.
• W1966193807 citedByCount "158" @default.
• W1966193807 countsByYear W19661938072012 @default.
• W1966193807 countsByYear W19661938072013 @default.
• W1966193807 countsByYear W19661938072014 @default.
• W1966193807 countsByYear W19661938072015 @default.
• W1966193807 countsByYear W19661938072016 @default.
• W1966193807 countsByYear W19661938072017 @default.
• W1966193807 countsByYear W19661938072018 @default.
• W1966193807 countsByYear W19661938072019 @default.
• W1966193807 countsByYear W19661938072020 @default.
• W1966193807 countsByYear W19661938072021 @default.
• W1966193807 countsByYear W19661938072022 @default.
• W1966193807 crossrefType "journal-article" @default.
• W1966193807 hasAuthorship W1966193807A5002994981 @default.
• W1966193807 hasAuthorship W1966193807A5005600452 @default.
• W1966193807 hasAuthorship W1966193807A5029530124 @default.
• W1966193807 hasAuthorship W1966193807A5061495260 @default.
• W1966193807 hasConcept C1491633281 @default.
• W1966193807 hasConcept C170493617 @default.
• W1966193807 hasConcept C180899940 @default.
• W1966193807 hasConcept C185592680 @default.
• W1966193807 hasConcept C2778918659 @default.
• W1966193807 hasConcept C41625074 @default.
• W1966193807 hasConcept C55493867 @default.
• W1966193807 hasConcept C58017582 @default.
• W1966193807 hasConcept C70721500 @default.
• W1966193807 hasConcept C86803240 @default.
• W1966193807 hasConcept C95444343 @default.
• W1966193807 hasConceptScore W1966193807C1491633281 @default.
• W1966193807 hasConceptScore W1966193807C170493617 @default.
• W1966193807 hasConceptScore W1966193807C180899940 @default.
• W1966193807 hasConceptScore W1966193807C185592680 @default.
• W1966193807 hasConceptScore W1966193807C2778918659 @default.
• W1966193807 hasConceptScore W1966193807C41625074 @default.
• W1966193807 hasConceptScore W1966193807C55493867 @default.
• W1966193807 hasConceptScore W1966193807C58017582 @default.
• W1966193807 hasConceptScore W1966193807C70721500 @default.
• W1966193807 hasConceptScore W1966193807C86803240 @default.
• W1966193807 hasConceptScore W1966193807C95444343 @default.
• W1966193807 hasIssue "2" @default.
• W1966193807 hasLocation W19661938071 @default.
• W1966193807 hasLocation W19661938072 @default.
• W1966193807 hasOpenAccess W1966193807 @default.
• W1966193807 hasPrimaryLocation W19661938071 @default.
• W1966193807 hasRelatedWork W2004558801 @default.
• W1966193807 hasRelatedWork W2017497567 @default.
• W1966193807 hasRelatedWork W2058243754 @default.
• W1966193807 hasRelatedWork W2061703312 @default.
• W1966193807 hasRelatedWork W2091512523 @default.
• W1966193807 hasRelatedWork W2117748922 @default.

• next