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- W1966197420 abstract "THERE are several reports of the effect of methylandrostenediol on the nitrogen metabolism of patients. There is evidence that methylandrostenediol (MAD) has a definite nitrogen-retaining effect in the human being. Talbot et al. (1) observed in a young female with Addison's disease a daily nitrogen retention of 50 mg. per Kg. of body weight, when she was given a daily oral dose of 50 mg. of MAD. In this same patient on the same diet, methyltestosterone in a daily oral dose of 25 mg. resulted in a nitrogen retention of 100 mg. daily per Kg. of body weight. In 1 out of 3 dwarfs Wilkins (2) observed a protein anabolic action of an oral dose of 30 mg. of MAD daily. Thorn (3) obtained a positive effect on the nitrogen balance in 4 patients, with 25 mg. of MAD intramuscularly. Homburger et al., (4) in comparing the nitrogen-retaining effect of MAD and testosterone, observed that 25 mg. of MAD daily for six days was about half as effective as the same amount of testosterone. No masculinizing effects were mention..." @default.
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- W1966197420 date "1952-08-01" @default.
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- W1966197420 title "A BALANCE STUDY OF METHYLANDROSTENEDIOL IN A PATIENT WITH HYPOGONADISM" @default.
- W1966197420 doi "https://doi.org/10.1210/jcem-12-8-1077" @default.
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