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- W1966226602 abstract "The purpose of this study was to compare the prevalence and implications of expiratory flow limitation (EFL) during exercise in boys and girls. Forty healthy, prepubescent boys (B; n = 20) and girls (G; n = 20) were tested. Subjects completed pulmonary function tests and an incremental cycle maximal oxygen uptake (V̇o 2max ) test. EFL was recorded at the end of each exercise stage using the % tidal volume overlap method. Ventilatory and metabolic data were recorded throughout exercise. Arterial oxygen saturation (Sp O 2 ) was determined via pulse oximetry. Body composition was determined using dual-energy X-ray absorptiometry. There were no differences ( P > 0.05) in height, weight, or body composition between boys and girls. At rest, boys had significantly higher lung volumes (total lung capacity, B = 2.6 ± 0.5 liters, G = 2.1 ± 0.5 liters) and peak expiratory flow rates (B = 3.6 ± 0.6 l/s; G = 1.6 ± 0.3 l/s). Boys also had significantly higher V̇o 2max (B = 46.9 ± 5.9 ml·kg lean body mass −1 ·min −1 , G = 41.7 ± 6.6 ml·kg lean body mass −1 ·min −1 ) and maximal ventilation (B = 49.8 ± 8.8 l/min, G = 41.2 ± 8.3 l/min) compared with girls. There were no sex differences ( P > 0.05) at V̇o 2max in VE /Vco 2 , end-tidal Pco 2 , heart rate, respiratory exchange ratio, or Sp O 2 . The prevalence (B = 19/20 vs. G = 18/20) and severity (B = 58 ± 7% vs. G = 43 ± 8% tidal volume) of EFL was not significantly different in boys compared with girls at V̇o 2max . A significant relationship existed between % EFL at V̇o 2max and the change in end-expiratory lung volume from rest to maximal exercise in boys ( r = 0.77) and girls ( r = 0.75). In summary, our data suggests that EFL is highly and equally prevalent in prepubescent boys and girls during heavy exercise, which led to an increased end-expiratory lung volume but not to decreases in arterial oxygen saturation." @default.
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- W1966226602 date "2010-05-01" @default.
- W1966226602 modified "2023-09-25" @default.
- W1966226602 title "Expiratory flow limitation during exercise in prepubescent boys and girls: prevalence and implications" @default.
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- W1966226602 doi "https://doi.org/10.1152/japplphysiol.00123.2009" @default.
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