Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966233783> ?p ?o ?g. }
- W1966233783 endingPage "37" @default.
- W1966233783 startingPage "28" @default.
- W1966233783 abstract "Problem MUC16 (CA125) released from ovarian tumors binds to NK cells and monocytes via the inhibitory receptor Siglec-9. Here, we investigate whether MUC16 also binds to circulating immune cells during pregnancy and in women with preeclampsia. Method of study MUC16 binding was monitored by flow cytometry and immunoprecipitation, and RT-PCR was used to monitor indigenous expression in immune cells. Serum CA125 levels were measured by a clinical assay. Results MUC16 was equally distributed on Siglec-9pos CD16pos/CD56dim and CD16neg/CD56br NK cells in the healthy pregnant and preeclampsia groups. While serum CA125 levels and number of NK and monocytes were similar, increased binding of MUC16 was observed on these immune cells in the preeclampsia cohort as compared to the healthy pregnant samples. Conclusion MUC16 binding to NK cells and monocytes likely contributes to tolerance of the fetal allograft from maternal responses and may also serve as a novel biomarker for preeclampsia." @default.
- W1966233783 created "2016-06-24" @default.
- W1966233783 creator A5005684133 @default.
- W1966233783 creator A5009470791 @default.
- W1966233783 creator A5013711340 @default.
- W1966233783 creator A5017296265 @default.
- W1966233783 creator A5027080762 @default.
- W1966233783 creator A5040947461 @default.
- W1966233783 creator A5053096187 @default.
- W1966233783 creator A5069778340 @default.
- W1966233783 date "2012-03-01" @default.
- W1966233783 modified "2023-10-17" @default.
- W1966233783 title "The Mucin MUC16 (CA125) Binds to NK Cells and Monocytes from Peripheral Blood of Women with Healthy Pregnancy and Preeclampsia" @default.
- W1966233783 cites W1489043436 @default.
- W1966233783 cites W1741227320 @default.
- W1966233783 cites W1966864407 @default.
- W1966233783 cites W1971426454 @default.
- W1966233783 cites W1972066637 @default.
- W1966233783 cites W1974963325 @default.
- W1966233783 cites W1977709543 @default.
- W1966233783 cites W1979568379 @default.
- W1966233783 cites W1982595711 @default.
- W1966233783 cites W2004619662 @default.
- W1966233783 cites W2006131167 @default.
- W1966233783 cites W2010011314 @default.
- W1966233783 cites W2012744533 @default.
- W1966233783 cites W2014947083 @default.
- W1966233783 cites W2016329950 @default.
- W1966233783 cites W2025635581 @default.
- W1966233783 cites W2026875502 @default.
- W1966233783 cites W2031145218 @default.
- W1966233783 cites W2036136429 @default.
- W1966233783 cites W2036520114 @default.
- W1966233783 cites W2037412915 @default.
- W1966233783 cites W2042350108 @default.
- W1966233783 cites W2047120971 @default.
- W1966233783 cites W2050396069 @default.
- W1966233783 cites W2054630820 @default.
- W1966233783 cites W2059450339 @default.
- W1966233783 cites W2062716052 @default.
- W1966233783 cites W2067187780 @default.
- W1966233783 cites W2072120276 @default.
- W1966233783 cites W2073870582 @default.
- W1966233783 cites W2087162329 @default.
- W1966233783 cites W2088279827 @default.
- W1966233783 cites W2089723143 @default.
- W1966233783 cites W2093060517 @default.
- W1966233783 cites W2093252833 @default.
- W1966233783 cites W2098419540 @default.
- W1966233783 cites W2100256708 @default.
- W1966233783 cites W2102719470 @default.
- W1966233783 cites W2109155665 @default.
- W1966233783 cites W2131331408 @default.
- W1966233783 cites W2131813152 @default.
- W1966233783 cites W2136753100 @default.
- W1966233783 cites W2150173080 @default.
- W1966233783 cites W2150312232 @default.
- W1966233783 cites W2158822102 @default.
- W1966233783 cites W2162763925 @default.
- W1966233783 cites W2166400341 @default.
- W1966233783 cites W2322713208 @default.
- W1966233783 cites W4244433662 @default.
- W1966233783 doi "https://doi.org/10.1111/j.1600-0897.2012.01113.x" @default.
- W1966233783 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3370110" @default.
- W1966233783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22380506" @default.
- W1966233783 hasPublicationYear "2012" @default.
- W1966233783 type Work @default.
- W1966233783 sameAs 1966233783 @default.
- W1966233783 citedByCount "27" @default.
- W1966233783 countsByYear W19662337832013 @default.
- W1966233783 countsByYear W19662337832014 @default.
- W1966233783 countsByYear W19662337832015 @default.
- W1966233783 countsByYear W19662337832016 @default.
- W1966233783 countsByYear W19662337832018 @default.
- W1966233783 countsByYear W19662337832019 @default.
- W1966233783 countsByYear W19662337832020 @default.
- W1966233783 countsByYear W19662337832021 @default.
- W1966233783 countsByYear W19662337832022 @default.
- W1966233783 countsByYear W19662337832023 @default.
- W1966233783 crossrefType "journal-article" @default.
- W1966233783 hasAuthorship W1966233783A5005684133 @default.
- W1966233783 hasAuthorship W1966233783A5009470791 @default.
- W1966233783 hasAuthorship W1966233783A5013711340 @default.
- W1966233783 hasAuthorship W1966233783A5017296265 @default.
- W1966233783 hasAuthorship W1966233783A5027080762 @default.
- W1966233783 hasAuthorship W1966233783A5040947461 @default.
- W1966233783 hasAuthorship W1966233783A5053096187 @default.
- W1966233783 hasAuthorship W1966233783A5069778340 @default.
- W1966233783 hasBestOaLocation W19662337832 @default.
- W1966233783 hasConcept C185592680 @default.
- W1966233783 hasConcept C203014093 @default.
- W1966233783 hasConcept C2777218350 @default.
- W1966233783 hasConcept C2778017598 @default.
- W1966233783 hasConcept C2779234561 @default.
- W1966233783 hasConcept C2781197716 @default.
- W1966233783 hasConcept C54355233 @default.
- W1966233783 hasConcept C553184892 @default.
- W1966233783 hasConcept C55493867 @default.