FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966254614> ?p ?o ?g. }

• W1966254614 endingPage "521" @default.
• W1966254614 startingPage "516" @default.
• W1966254614 abstract "Amantadine-sensitive proton uptake by liposomes is currently the preferred method of demonstrating M2 functionality after reconstitution, to validate structural determination with techniques such as solid-state NMR. With strong driving forces (two decades each of both [K+] gradient-induced membrane potential and [H+] gradient), M2(22–62) showed a transport rate of 78 H+/tetramer-s (pHo 6.0, pHi 8.0, nominal Vm = −114 mV), higher than previously measured for similar, shorter, and full-length constructs. Amantadine sensitivity of the conductance domain at pH 6.8 was also comparable to other published reports. Proton flux rate was optimal at protein densities of 0.05–1.0% (peptide wt.% in lipid). Rundown of total proton uptake after addition of valinomycin and CCCP, as detected by delayed addition of valinomycin, indicated M2-induced K+ flux of 0.1 K+/tetramer-s, and also demonstrated that the K+ permeability, relative to H+, was 2.8 × 10− 6. Transport rate, amantadine and cyclooctylamine sensitivity, acid activation, and H+ selectivity were all consistent with full functionality of the reconstituted conductance domain. Decreased external pH increased proton uptake with an apparent pKa of 6." @default.
• W1966254614 created "2016-06-24" @default.
• W1966254614 creator A5020704363 @default.
• W1966254614 creator A5026225593 @default.
• W1966254614 creator A5027395813 @default.
• W1966254614 creator A5027989001 @default.
• W1966254614 creator A5038473475 @default.
• W1966254614 creator A5043609460 @default.
• W1966254614 creator A5052551630 @default.
• W1966254614 creator A5075658290 @default.
• W1966254614 date "2011-02-01" @default.
• W1966254614 modified "2023-10-16" @default.
• W1966254614 title "Functional reconstitution of influenza A M2(22–62)" @default.
• W1966254614 cites W1536496588 @default.
• W1966254614 cites W1585610099 @default.
• W1966254614 cites W1965325224 @default.
• W1966254614 cites W1970960203 @default.
• W1966254614 cites W1972065621 @default.
• W1966254614 cites W1975415559 @default.
• W1966254614 cites W1979262025 @default.
• W1966254614 cites W1987413552 @default.
• W1966254614 cites W1988031737 @default.
• W1966254614 cites W1994015011 @default.
• W1966254614 cites W2001099462 @default.
• W1966254614 cites W2004067557 @default.
• W1966254614 cites W2004124445 @default.
• W1966254614 cites W2008617981 @default.
• W1966254614 cites W2011794608 @default.
• W1966254614 cites W2034453538 @default.
• W1966254614 cites W2041995729 @default.
• W1966254614 cites W2043149972 @default.
• W1966254614 cites W2045053284 @default.
• W1966254614 cites W2063012912 @default.
• W1966254614 cites W2071135420 @default.
• W1966254614 cites W2074499311 @default.
• W1966254614 cites W2079298235 @default.
• W1966254614 cites W2097980158 @default.
• W1966254614 cites W2099344204 @default.
• W1966254614 cites W2108981195 @default.
• W1966254614 cites W2109910734 @default.
• W1966254614 cites W2110733672 @default.
• W1966254614 cites W2128375777 @default.
• W1966254614 cites W2160841393 @default.
• W1966254614 cites W2280575739 @default.
• W1966254614 doi "https://doi.org/10.1016/j.bbamem.2010.10.010" @default.
• W1966254614 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3005097" @default.
• W1966254614 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20969830" @default.
• W1966254614 hasPublicationYear "2011" @default.
• W1966254614 type Work @default.
• W1966254614 sameAs 1966254614 @default.
• W1966254614 citedByCount "18" @default.
• W1966254614 countsByYear W19662546142012 @default.
• W1966254614 countsByYear W19662546142013 @default.
• W1966254614 countsByYear W19662546142014 @default.
• W1966254614 countsByYear W19662546142015 @default.
• W1966254614 countsByYear W19662546142016 @default.
• W1966254614 countsByYear W19662546142018 @default.
• W1966254614 countsByYear W19662546142020 @default.
• W1966254614 countsByYear W19662546142021 @default.
• W1966254614 countsByYear W19662546142023 @default.
• W1966254614 crossrefType "journal-article" @default.
• W1966254614 hasAuthorship W1966254614A5020704363 @default.
• W1966254614 hasAuthorship W1966254614A5026225593 @default.
• W1966254614 hasAuthorship W1966254614A5027395813 @default.
• W1966254614 hasAuthorship W1966254614A5027989001 @default.
• W1966254614 hasAuthorship W1966254614A5038473475 @default.
• W1966254614 hasAuthorship W1966254614A5043609460 @default.
• W1966254614 hasAuthorship W1966254614A5052551630 @default.
• W1966254614 hasAuthorship W1966254614A5075658290 @default.
• W1966254614 hasBestOaLocation W19662546141 @default.
• W1966254614 hasConcept C114614502 @default.
• W1966254614 hasConcept C118792377 @default.
• W1966254614 hasConcept C120882062 @default.
• W1966254614 hasConcept C121332964 @default.
• W1966254614 hasConcept C121932024 @default.
• W1966254614 hasConcept C12554922 @default.
• W1966254614 hasConcept C161790260 @default.
• W1966254614 hasConcept C181199279 @default.
• W1966254614 hasConcept C185592680 @default.
• W1966254614 hasConcept C2778385715 @default.
• W1966254614 hasConcept C2778886173 @default.
• W1966254614 hasConcept C33923547 @default.
• W1966254614 hasConcept C41625074 @default.
• W1966254614 hasConcept C54516573 @default.
• W1966254614 hasConcept C55493867 @default.
• W1966254614 hasConcept C62520636 @default.
• W1966254614 hasConcept C86803240 @default.
• W1966254614 hasConcept C90424259 @default.
• W1966254614 hasConceptScore W1966254614C114614502 @default.
• W1966254614 hasConceptScore W1966254614C118792377 @default.
• W1966254614 hasConceptScore W1966254614C120882062 @default.
• W1966254614 hasConceptScore W1966254614C121332964 @default.
• W1966254614 hasConceptScore W1966254614C121932024 @default.
• W1966254614 hasConceptScore W1966254614C12554922 @default.
• W1966254614 hasConceptScore W1966254614C161790260 @default.
• W1966254614 hasConceptScore W1966254614C181199279 @default.
• W1966254614 hasConceptScore W1966254614C185592680 @default.
• W1966254614 hasConceptScore W1966254614C2778385715 @default.

• next