Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966257377> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W1966257377 endingPage "6a" @default.
- W1966257377 startingPage "6a" @default.
- W1966257377 abstract "The TrkH/TrkG/KtrB family of proteins mediate K+ uptake in bacteria and likely evolved from simple K+ channels by multiple gene duplications or fusions. We have solved the crystal structure of a TrkH from Vibrio parahaemolyticus to 3.5 Å. TrkH is a homodimer, and each protomer contains an ion permeation pathway. A selectivity filter, similar in architecture to that in K+ channels but significantly shorter, is lined by backbone and side chain oxygen atoms. Functional studies showed that TrkH allows permeation of K+ and Rb+ but not smaller ions such as Na+ or Li+. Immediately intracellular to the selectivity filter is an intramembrane loop and an arginine residue, both highly conserved, that constrict an otherwise open permeation pathway. Functions of the loop and the positive charge (Arg) will be addressed." @default.
- W1966257377 created "2016-06-24" @default.
- W1966257377 creator A5056870218 @default.
- W1966257377 date "2011-02-01" @default.
- W1966257377 modified "2023-09-27" @default.
- W1966257377 title "Ion Selectivity and Permeation in a Potassium Ion Transporter" @default.
- W1966257377 doi "https://doi.org/10.1016/j.bpj.2010.12.245" @default.
- W1966257377 hasPublicationYear "2011" @default.
- W1966257377 type Work @default.
- W1966257377 sameAs 1966257377 @default.
- W1966257377 citedByCount "0" @default.
- W1966257377 crossrefType "journal-article" @default.
- W1966257377 hasAuthorship W1966257377A5056870218 @default.
- W1966257377 hasBestOaLocation W19662573771 @default.
- W1966257377 hasConcept C104317684 @default.
- W1966257377 hasConcept C118792377 @default.
- W1966257377 hasConcept C12554922 @default.
- W1966257377 hasConcept C145148216 @default.
- W1966257377 hasConcept C149011108 @default.
- W1966257377 hasConcept C161790260 @default.
- W1966257377 hasConcept C170493617 @default.
- W1966257377 hasConcept C178790620 @default.
- W1966257377 hasConcept C185592680 @default.
- W1966257377 hasConcept C204921945 @default.
- W1966257377 hasConcept C41625074 @default.
- W1966257377 hasConcept C50254741 @default.
- W1966257377 hasConcept C50670333 @default.
- W1966257377 hasConcept C512185932 @default.
- W1966257377 hasConcept C517785266 @default.
- W1966257377 hasConcept C521977710 @default.
- W1966257377 hasConcept C55493867 @default.
- W1966257377 hasConcept C79879829 @default.
- W1966257377 hasConcept C86803240 @default.
- W1966257377 hasConceptScore W1966257377C104317684 @default.
- W1966257377 hasConceptScore W1966257377C118792377 @default.
- W1966257377 hasConceptScore W1966257377C12554922 @default.
- W1966257377 hasConceptScore W1966257377C145148216 @default.
- W1966257377 hasConceptScore W1966257377C149011108 @default.
- W1966257377 hasConceptScore W1966257377C161790260 @default.
- W1966257377 hasConceptScore W1966257377C170493617 @default.
- W1966257377 hasConceptScore W1966257377C178790620 @default.
- W1966257377 hasConceptScore W1966257377C185592680 @default.
- W1966257377 hasConceptScore W1966257377C204921945 @default.
- W1966257377 hasConceptScore W1966257377C41625074 @default.
- W1966257377 hasConceptScore W1966257377C50254741 @default.
- W1966257377 hasConceptScore W1966257377C50670333 @default.
- W1966257377 hasConceptScore W1966257377C512185932 @default.
- W1966257377 hasConceptScore W1966257377C517785266 @default.
- W1966257377 hasConceptScore W1966257377C521977710 @default.
- W1966257377 hasConceptScore W1966257377C55493867 @default.
- W1966257377 hasConceptScore W1966257377C79879829 @default.
- W1966257377 hasConceptScore W1966257377C86803240 @default.
- W1966257377 hasIssue "3" @default.
- W1966257377 hasLocation W19662573771 @default.
- W1966257377 hasOpenAccess W1966257377 @default.
- W1966257377 hasPrimaryLocation W19662573771 @default.
- W1966257377 hasRelatedWork W1967113088 @default.
- W1966257377 hasRelatedWork W2007150583 @default.
- W1966257377 hasRelatedWork W2014982828 @default.
- W1966257377 hasRelatedWork W2031770611 @default.
- W1966257377 hasRelatedWork W2034922610 @default.
- W1966257377 hasRelatedWork W2738703249 @default.
- W1966257377 hasRelatedWork W3045230774 @default.
- W1966257377 hasRelatedWork W3200088880 @default.
- W1966257377 hasRelatedWork W4200570478 @default.
- W1966257377 hasRelatedWork W4224260353 @default.
- W1966257377 hasVolume "100" @default.
- W1966257377 isParatext "false" @default.
- W1966257377 isRetracted "false" @default.
- W1966257377 magId "1966257377" @default.
- W1966257377 workType "article" @default.