FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966276140> ?p ?o ?g. }

• W1966276140 endingPage "26" @default.
• W1966276140 startingPage "13" @default.
• W1966276140 abstract "Numerous studies have provided evidence for a direct functional link between the renin-angiotensin-aldosterone system and the fibrinolytic system. Angiotensin II has been suggested to mediate this interrelationship because this peptide was shown to stimulate plasminogen activator inhibitor-1 (PAI-1) in experimental settings. However, evidence from studies in man regarding effects of Angiotensin II on fibrinolytic function remains controversial.In the present study, we have therefore infused Angiotensin II at doses of 1, 3 and 10 ng kg(-1) min(-1), each over 45 min, in 9 healthy volunteer subjects without and with pretreatment with a single dose of the Angiotensin II (type 1) (AT1)-receptor antagonist valsartan (160 mg).Angiotensin II infusion dose-dependently increased plasma Angiotensin II concentrations and systolic/diastolic arterial blood pressure from 121 +/- 2/70 +/- 2 mmHg to 146 +/- 2/97 +/- 1 mmHg (p < 0.001). The maximum increase in blood pressure was completely abolished (118 +/- 3/72 +/- 1 mmHg) when Angiotensin II was infused in volunteers pretreated with valsartan. In spite of the marked hemodynamic changes seen with the Angiotensin II infusion, no effect could be demonstrated on the activity and antigen concentration of PAI-1. Furthermore, pretreatment of the volunteers with valsartan markedly blunted the increase in arterial blood pressure but was not associated with changes in PAI-1.In conclusion, in healthy volunteer subjects, short-term infusion of Angiotensin II without and with concomitant administration of an AT1-receptor antagonist has no effect on PAI-1 activities and plasma concentrations." @default.
• W1966276140 created "2016-06-24" @default.
• W1966276140 creator A5000764134 @default.
• W1966276140 creator A5010271819 @default.
• W1966276140 creator A5040729270 @default.
• W1966276140 creator A5055002837 @default.
• W1966276140 creator A5086661016 @default.
• W1966276140 date "2004-01-01" @default.
• W1966276140 modified "2023-09-26" @default.
• W1966276140 title "Short‐Term Effects of Exogenous Angiotensin II on Plasma Fibrinolytic Balance in Normal Subjects" @default.
• W1966276140 cites W1975622210 @default.
• W1966276140 cites W1983416483 @default.
• W1966276140 cites W1984604323 @default.
• W1966276140 cites W1998873687 @default.
• W1966276140 cites W2009102597 @default.
• W1966276140 cites W2014870763 @default.
• W1966276140 cites W2015273569 @default.
• W1966276140 cites W2021003600 @default.
• W1966276140 cites W2022352282 @default.
• W1966276140 cites W2055420779 @default.
• W1966276140 cites W2056744803 @default.
• W1966276140 cites W2062198708 @default.
• W1966276140 cites W2064359315 @default.
• W1966276140 cites W2074384719 @default.
• W1966276140 cites W2076907458 @default.
• W1966276140 cites W2085927807 @default.
• W1966276140 cites W2097489256 @default.
• W1966276140 cites W2097552698 @default.
• W1966276140 cites W2108648731 @default.
• W1966276140 cites W2112208424 @default.
• W1966276140 cites W2119869567 @default.
• W1966276140 cites W2141019187 @default.
• W1966276140 cites W2148688310 @default.
• W1966276140 cites W2163510728 @default.
• W1966276140 cites W2312388685 @default.
• W1966276140 cites W2342067247 @default.
• W1966276140 cites W2426848337 @default.
• W1966276140 cites W2585382523 @default.
• W1966276140 cites W4205373146 @default.
• W1966276140 cites W4237073742 @default.
• W1966276140 doi "https://doi.org/10.1081/ceh-120027328" @default.
• W1966276140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15000294" @default.
• W1966276140 hasPublicationYear "2004" @default.
• W1966276140 type Work @default.
• W1966276140 sameAs 1966276140 @default.
• W1966276140 citedByCount "13" @default.
• W1966276140 countsByYear W19662761402013 @default.
• W1966276140 countsByYear W19662761402015 @default.
• W1966276140 countsByYear W19662761402016 @default.
• W1966276140 countsByYear W19662761402018 @default.
• W1966276140 countsByYear W19662761402019 @default.
• W1966276140 countsByYear W19662761402021 @default.
• W1966276140 crossrefType "journal-article" @default.
• W1966276140 hasAuthorship W1966276140A5000764134 @default.
• W1966276140 hasAuthorship W1966276140A5010271819 @default.
• W1966276140 hasAuthorship W1966276140A5040729270 @default.
• W1966276140 hasAuthorship W1966276140A5055002837 @default.
• W1966276140 hasAuthorship W1966276140A5086661016 @default.
• W1966276140 hasConcept C104849204 @default.
• W1966276140 hasConcept C123915805 @default.
• W1966276140 hasConcept C126322002 @default.
• W1966276140 hasConcept C134018914 @default.
• W1966276140 hasConcept C185592680 @default.
• W1966276140 hasConcept C198710026 @default.
• W1966276140 hasConcept C2777387769 @default.
• W1966276140 hasConcept C2779679481 @default.
• W1966276140 hasConcept C2780708007 @default.
• W1966276140 hasConcept C2908929049 @default.
• W1966276140 hasConcept C71924100 @default.
• W1966276140 hasConcept C84393581 @default.
• W1966276140 hasConceptScore W1966276140C104849204 @default.
• W1966276140 hasConceptScore W1966276140C123915805 @default.
• W1966276140 hasConceptScore W1966276140C126322002 @default.
• W1966276140 hasConceptScore W1966276140C134018914 @default.
• W1966276140 hasConceptScore W1966276140C185592680 @default.
• W1966276140 hasConceptScore W1966276140C198710026 @default.
• W1966276140 hasConceptScore W1966276140C2777387769 @default.
• W1966276140 hasConceptScore W1966276140C2779679481 @default.
• W1966276140 hasConceptScore W1966276140C2780708007 @default.
• W1966276140 hasConceptScore W1966276140C2908929049 @default.
• W1966276140 hasConceptScore W1966276140C71924100 @default.
• W1966276140 hasConceptScore W1966276140C84393581 @default.
• W1966276140 hasIssue "1" @default.
• W1966276140 hasLocation W19662761401 @default.
• W1966276140 hasLocation W19662761402 @default.
• W1966276140 hasOpenAccess W1966276140 @default.
• W1966276140 hasPrimaryLocation W19662761401 @default.
• W1966276140 hasRelatedWork W1966276140 @default.
• W1966276140 hasRelatedWork W1974641745 @default.
• W1966276140 hasRelatedWork W1975191429 @default.
• W1966276140 hasRelatedWork W2021014823 @default.
• W1966276140 hasRelatedWork W2069855804 @default.
• W1966276140 hasRelatedWork W2126797993 @default.
• W1966276140 hasRelatedWork W2145797508 @default.
• W1966276140 hasRelatedWork W2334208166 @default.
• W1966276140 hasRelatedWork W3193972101 @default.
• W1966276140 hasRelatedWork W4247631657 @default.
• W1966276140 hasVolume "26" @default.

• next