FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966295551> ?p ?o ?g. }

• W1966295551 endingPage "184" @default.
• W1966295551 startingPage "179" @default.
• W1966295551 abstract "It is known that the metabolism of testosterone in the brain and in the anterior pituitary is different in mammalian and in photoperiodic avian species. In many mammalian species, testosterone is mainly metabolized to 5-α -reduced compounds (e.g. 17-β-hydroxy-5-α -androstan- 3-one, 5α -DHT and 3-α,17-β-dihydroxy-5-α -androstane, 5-α,3-α-diol) and, to a smaller extent, to 4-androstene-3,17-dione (androstenedione), while in birds, androstenedione is the main testosterone metabolite and the conversion to the 5-α -reduced compounds is quantitatively negligible. In avian species, testosterone is also converted to 5-β-reduced steroids (mainly 17-β-hydroxy-5-β-androstan-3-one, 5-β-DHT and 3-a,17-β-dihydroxy-5-β-androstane, 5-β,3-α -diol), and there is also evidence that in these species testosterone metabolism in the central structures may be influenced by the photoperiod. Since the hamster is a mammal whose reproductive cycle is controlled by day length, it has been analyzed whether: (a) the central structures of the hamster (cerebral cortex, hypothalamus and anterior pituitary) metabolize testosterone in vitro following a mammalian (5-α -reduced derivatives) or an avian (androstenedione and 5-β-reduced compounds) pattern; and (b) the metabolism of testosterone in the same structures may be modified by the exposure to different photoperiods (LD 14:10 or LD 8:16). The present data indicate that no one of the hamster structures examined produces the 5-β-reduced derivatives. Moreover, the formation of the 5α -DHT is quantitatively low, and is not affected by the photoperiod. In contrast, androstenedione is formed in quite high yields and the exposure of the animals to 60 days of short photostimulation increases the formation of this steroid in the pituitary gland, but not in the brain structures. From these data, it appears that the central structures of the hamster metabolize testosterone with a pattern which is intermediate between that of birds and mammals." @default.
• W1966295551 created "2016-06-24" @default.
• W1966295551 creator A5005948227 @default.
• W1966295551 creator A5008522126 @default.
• W1966295551 creator A5049310505 @default.
• W1966295551 creator A5070271118 @default.
• W1966295551 date "1987-08-01" @default.
• W1966295551 modified "2023-10-17" @default.
• W1966295551 title "Androgen metabolism in the male hamster—1. Metabolism of testosterone in the pituitary gland and in the brain of animals exposed to different photoperiods" @default.
• W1966295551 cites W1970614506 @default.
• W1966295551 cites W1971523281 @default.
• W1966295551 cites W1972456243 @default.
• W1966295551 cites W1987185277 @default.
• W1966295551 cites W1987900401 @default.
• W1966295551 cites W2003474543 @default.
• W1966295551 cites W2012757283 @default.
• W1966295551 cites W2023069284 @default.
• W1966295551 cites W2023194848 @default.
• W1966295551 cites W202556723 @default.
• W1966295551 cites W2032458171 @default.
• W1966295551 cites W2045692231 @default.
• W1966295551 cites W2053163348 @default.
• W1966295551 cites W2056990435 @default.
• W1966295551 cites W2057535584 @default.
• W1966295551 cites W2068670553 @default.
• W1966295551 cites W2068726469 @default.
• W1966295551 cites W2082313181 @default.
• W1966295551 cites W2083533622 @default.
• W1966295551 cites W2089294980 @default.
• W1966295551 cites W2091603292 @default.
• W1966295551 cites W2092196025 @default.
• W1966295551 cites W2131730508 @default.
• W1966295551 cites W2142998642 @default.
• W1966295551 cites W2144386498 @default.
• W1966295551 cites W2145874477 @default.
• W1966295551 cites W2157911393 @default.
• W1966295551 cites W2265390621 @default.
• W1966295551 cites W2316453664 @default.
• W1966295551 cites W49459440 @default.
• W1966295551 doi "https://doi.org/10.1016/0022-4731(87)90374-8" @default.
• W1966295551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3626554" @default.
• W1966295551 hasPublicationYear "1987" @default.
• W1966295551 type Work @default.
• W1966295551 sameAs 1966295551 @default.
• W1966295551 citedByCount "9" @default.
• W1966295551 crossrefType "journal-article" @default.
• W1966295551 hasAuthorship W1966295551A5005948227 @default.
• W1966295551 hasAuthorship W1966295551A5008522126 @default.
• W1966295551 hasAuthorship W1966295551A5049310505 @default.
• W1966295551 hasAuthorship W1966295551A5070271118 @default.
• W1966295551 hasConcept C126322002 @default.
• W1966295551 hasConcept C134018914 @default.
• W1966295551 hasConcept C185592680 @default.
• W1966295551 hasConcept C2776683971 @default.
• W1966295551 hasConcept C2777003273 @default.
• W1966295551 hasConcept C2777477808 @default.
• W1966295551 hasConcept C2777911890 @default.
• W1966295551 hasConcept C2778575167 @default.
• W1966295551 hasConcept C2779279991 @default.
• W1966295551 hasConcept C62231903 @default.
• W1966295551 hasConcept C71315377 @default.
• W1966295551 hasConcept C71924100 @default.
• W1966295551 hasConcept C86803240 @default.
• W1966295551 hasConceptScore W1966295551C126322002 @default.
• W1966295551 hasConceptScore W1966295551C134018914 @default.
• W1966295551 hasConceptScore W1966295551C185592680 @default.
• W1966295551 hasConceptScore W1966295551C2776683971 @default.
• W1966295551 hasConceptScore W1966295551C2777003273 @default.
• W1966295551 hasConceptScore W1966295551C2777477808 @default.
• W1966295551 hasConceptScore W1966295551C2777911890 @default.
• W1966295551 hasConceptScore W1966295551C2778575167 @default.
• W1966295551 hasConceptScore W1966295551C2779279991 @default.
• W1966295551 hasConceptScore W1966295551C62231903 @default.
• W1966295551 hasConceptScore W1966295551C71315377 @default.
• W1966295551 hasConceptScore W1966295551C71924100 @default.
• W1966295551 hasConceptScore W1966295551C86803240 @default.
• W1966295551 hasIssue "2" @default.
• W1966295551 hasLocation W19662955511 @default.
• W1966295551 hasLocation W19662955512 @default.
• W1966295551 hasOpenAccess W1966295551 @default.
• W1966295551 hasPrimaryLocation W19662955511 @default.
• W1966295551 hasRelatedWork W1986311037 @default.
• W1966295551 hasRelatedWork W1987914672 @default.
• W1966295551 hasRelatedWork W2012070670 @default.
• W1966295551 hasRelatedWork W2019346053 @default.
• W1966295551 hasRelatedWork W2030295611 @default.
• W1966295551 hasRelatedWork W2036404189 @default.
• W1966295551 hasRelatedWork W2060300693 @default.
• W1966295551 hasRelatedWork W2089368232 @default.
• W1966295551 hasRelatedWork W2094630696 @default.
• W1966295551 hasRelatedWork W2144746424 @default.
• W1966295551 hasVolume "28" @default.
• W1966295551 isParatext "false" @default.
• W1966295551 isRetracted "false" @default.
• W1966295551 magId "1966295551" @default.
• W1966295551 workType "article" @default.