Matches in SemOpenAlex for { <https://semopenalex.org/work/W1966296076> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W1966296076 endingPage "91" @default.
- W1966296076 startingPage "83" @default.
- W1966296076 abstract "The 4-, 7-, and 8-oxo-sialic acid β-methyl ketosides 7, 10a, and 11a were obtained by transformation of easily available derivatives of N-acetylneuraminic acid (1a). The carbonyl migration from C-7 to C-8 can be carried out under well-defined conditions with formation of the ketone 11b. Starting from 7- and 8-ketones 17 and 20 the corresponding dimethyl acetals are prepared. The 4-ketone 7 behaves as a moderate competitive inhibitor of CMP-sialate synthase [EC 2.7.7.43], whereas the 8-ketone 11a, the 8,8-dimethyl acetal 19, and the 7,7-dimethyl acetal 23 prove not to be inhibitors of this enzyme. The 7-ketone 10a was not tested because of instability under test conditions at pH 8.5." @default.
- W1966296076 created "2016-06-24" @default.
- W1966296076 creator A5023246805 @default.
- W1966296076 creator A5032109402 @default.
- W1966296076 creator A5063787147 @default.
- W1966296076 date "1990-01-22" @default.
- W1966296076 modified "2023-10-17" @default.
- W1966296076 title "Structural variations ofN-acetylneuraminic acid, 14. Synthesis of the β-methyl ketosides of 4-oxo-, 7-oxo-, and 8-oxo-N-acetylneuraminic acid and the corresponding 7,7- and 8,8-dimethoxy derivatives their behaviour towards CMP-sialate synthase" @default.
- W1966296076 cites W1560568906 @default.
- W1966296076 cites W1575467003 @default.
- W1966296076 cites W1968777330 @default.
- W1966296076 cites W1973315202 @default.
- W1966296076 cites W1979978407 @default.
- W1966296076 cites W2013853882 @default.
- W1966296076 cites W2017453494 @default.
- W1966296076 cites W2037582271 @default.
- W1966296076 cites W2043292636 @default.
- W1966296076 cites W2044413221 @default.
- W1966296076 cites W2069607377 @default.
- W1966296076 cites W2315841837 @default.
- W1966296076 cites W2324017414 @default.
- W1966296076 cites W2328630969 @default.
- W1966296076 cites W2334055901 @default.
- W1966296076 cites W2398032887 @default.
- W1966296076 doi "https://doi.org/10.1002/jlac.199019900112" @default.
- W1966296076 hasPublicationYear "1990" @default.
- W1966296076 type Work @default.
- W1966296076 sameAs 1966296076 @default.
- W1966296076 citedByCount "21" @default.
- W1966296076 countsByYear W19662960762014 @default.
- W1966296076 crossrefType "journal-article" @default.
- W1966296076 hasAuthorship W1966296076A5023246805 @default.
- W1966296076 hasAuthorship W1966296076A5032109402 @default.
- W1966296076 hasAuthorship W1966296076A5063787147 @default.
- W1966296076 hasConcept C155647269 @default.
- W1966296076 hasConcept C178790620 @default.
- W1966296076 hasConcept C185592680 @default.
- W1966296076 hasConcept C2777731525 @default.
- W1966296076 hasConcept C2777738585 @default.
- W1966296076 hasConcept C2778671442 @default.
- W1966296076 hasConcept C2780115458 @default.
- W1966296076 hasConcept C2908682898 @default.
- W1966296076 hasConcept C31532488 @default.
- W1966296076 hasConcept C55493867 @default.
- W1966296076 hasConcept C62231903 @default.
- W1966296076 hasConcept C71240020 @default.
- W1966296076 hasConceptScore W1966296076C155647269 @default.
- W1966296076 hasConceptScore W1966296076C178790620 @default.
- W1966296076 hasConceptScore W1966296076C185592680 @default.
- W1966296076 hasConceptScore W1966296076C2777731525 @default.
- W1966296076 hasConceptScore W1966296076C2777738585 @default.
- W1966296076 hasConceptScore W1966296076C2778671442 @default.
- W1966296076 hasConceptScore W1966296076C2780115458 @default.
- W1966296076 hasConceptScore W1966296076C2908682898 @default.
- W1966296076 hasConceptScore W1966296076C31532488 @default.
- W1966296076 hasConceptScore W1966296076C55493867 @default.
- W1966296076 hasConceptScore W1966296076C62231903 @default.
- W1966296076 hasConceptScore W1966296076C71240020 @default.
- W1966296076 hasIssue "1" @default.
- W1966296076 hasLocation W19662960761 @default.
- W1966296076 hasOpenAccess W1966296076 @default.
- W1966296076 hasPrimaryLocation W19662960761 @default.
- W1966296076 hasRelatedWork W1966296076 @default.
- W1966296076 hasRelatedWork W1971190669 @default.
- W1966296076 hasRelatedWork W1977905034 @default.
- W1966296076 hasRelatedWork W2159496072 @default.
- W1966296076 hasRelatedWork W2409447467 @default.
- W1966296076 hasRelatedWork W2907066173 @default.
- W1966296076 hasRelatedWork W2953130490 @default.
- W1966296076 hasRelatedWork W4249685300 @default.
- W1966296076 hasRelatedWork W4256332778 @default.
- W1966296076 hasRelatedWork W2033599146 @default.
- W1966296076 hasVolume "1990" @default.
- W1966296076 isParatext "false" @default.
- W1966296076 isRetracted "false" @default.
- W1966296076 magId "1966296076" @default.
- W1966296076 workType "article" @default.