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- W1966317077 abstract "Preeclampsia is a major cause of maternal and fetal morbidity and mortality worldwide, however, its etiology remains unclear. Abnormal placental angiogenesis during pregnancy resulting from high levels of anti-angiogenic factors, soluble Flt1 (sFlt1) and soluble endoglin (sEng) has been implicated in preeclampsia pathogenesis. Accumulating evidence also points to a role for these anti-angiogenic proteins as serum biomarkers for the clinical diagnosis and prediction of preeclampsia. Uncovering the mechanisms of altered angiogenic factors in preeclampsia may also provide insights into novel preventive and therapeutic options." @default.
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- W1966317077 date "2011-01-01" @default.
- W1966317077 modified "2023-09-26" @default.
- W1966317077 title "Preeclampsia and the anti-angiogenic state" @default.
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- W1966317077 doi "https://doi.org/10.1016/j.preghy.2010.10.007" @default.
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